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- Table of Contents
Endoglin Antibodies
AND ENG ELISA kits, Endoglin Proteins
Many biological assays use antibodies to detect Endoglin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endoglin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endoglin antibodies...
Designing a Western blot for Endoglin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ENG Western Blot GuideENG Infographic by Boster Bio
All ENG Products
Product
Figures
Specificity
Applications
Price
Anti-CD105/ENG Antibody Picoband®
4 Citations
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A02997-3
100 μg/vial
Cat # A02997-3
100 μg/vial
Human
ELISA
$499
Cat # EK0644
96 wells/kit, with removable strips.
Cat # EK0644
96 wells/kit, with removable strips.
Anti-CD105/Eng Antibody Picoband®
3 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A02997-2
100 μg/vial
Cat # A02997-2
100 μg/vial
Human
ELISA
$500
Cat # EZ0644
5 plates/kit
Cat # EZ0644
5 plates/kit
Anti-CACNA1S Antibody Picoband®
1 Citations
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03006-1
100 μg/vial
Cat # A03006-1
100 μg/vial
Human
ELISA
$499
Cat # FEK0644
96 wells/kit, with removable strips.
Cat # FEK0644
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03001-1
100 µg/vial
Cat # A03001-1
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M05395
100 μl/vial
Cat # M05395
100 μl/vial
Human
IF, WB
$523
Cat # M02997-4
100 µl
Cat # M02997-4
100 µl
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M02997-8
20μL, 40μL, 100μL, 200μL
Cat # M02997-8
20μL, 40μL, 100μL, 200μL
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02997-6
100 μg
Cat # M02997-6
100 μg
Human, Pig
Flow Cytometry, IHC-F, ICC, WB
$301
Cat # M02997-2
0.1 mg
Cat # M02997-2
0.1 mg
Human, Rat
Flow Cytometry, IP, WB, CyTOF
$301
Cat # M02997-1
0.1 mg
Cat # M02997-1
0.1 mg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02997-7
100 μg
Cat # M02997-7
100 μg
Mouse
Flow Cytometry, IP, IHC-F, WB
$301
Cat # M02997-3
0.1 mg
Cat # M02997-3
0.1 mg
ENG Overview
Facts about Endoglin.
Endoglin (ENG)
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529). Required for normal structure and ethics of adult vasculature (PubMed:7894484).
Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | ENG |
| Uniprot: | P17813 |
| Entrez: | 2022 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD105 antigen; CD105; Endoglin; ENDOsler-Rendu-Weber syndrome 1; ENG; HHT1FLJ41744; ORW; ORW1
Molecular Weight
Mass (kDA):
70.578 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.11 |
| Sequence: | 9; NC_000009.12 (127815012..127854773, complement) |
Tissue Specificity
Detected on umbilical veil endothelial cells (PubMed:10625079). Detected in placenta (at protein level) (PubMed:1692830). Detected on endothelial cells (PubMed:1692830).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Tumor Angiogenesis
- Pathologic Neovascularization
- Malignant Neoplasms
- Hereditary Hemorrhagic Telangiectasia
- Telangiectasis
- Pre-eclampsia
- Carcinoma
- Neoplasm Metastasis
- Arteriovenous Malformation
- Tissue Adhesions
- Hypertensive Disease
- Vascular Diseases
Interacting Proteins
- ITGA5
- ITGB1
- LRG1
- TGFB1
Pathways
- Angiogenesis
- Pathogenesis
- Cell Proliferation
- Localization
- Cell Adhesion
- Secretion
- Regeneration
- Transport
- Cell Growth
- Translation
- Cell Migration
- Vasculogenesis
- Fermentation
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Oxidation
- Dephosphorylation
- Methylation
- Demethylation
Research Areas
- Cancer
- Cell Biology
- Cellular Markers
- Endothelial Cell Markers
- Extracellular Matrix
- Hypoxia
- Immunology
- Mesenchymal Stem Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENG
bosterbio.com/bosterbio-gene-info-cards/ENG
References
PMID: 8370410 by Bellon T., et al. Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions.
PMID: 1692830 by Gougos A., et al. Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.
12 Publications of Boster Endoglin Antibodies & ELISA Kits
- PubMed ID: , Engineering Stem Cell Derived Biomimetic Vesicles for Versatility and Effective ...
- PubMed ID: -, Wu,H.,Jiang,X.,Li,Y.,Zhou,Y.,Zhang,T.,Zhi,P.,Gao,J.,Engineering Stem Cell Derive...
- PubMed ID: 30806029 , CFTR dysfunction increases endoglin and TGF-β signaling in airway epithelia
- PubMed ID: 28147322, VEGF promotes cartilage angiogenesis by phospho-ERK1/2 activation of Dll4 signal...
- PubMed ID: 26807166, Effects of human umbilical cord mesenchymal stem cell transplantation combined w...
- PubMed ID: 24824427, Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improve...
- PubMed ID: 26797779, Overexpression of transcription factor Foxa2 and Hnf1? induced rat bone mesenchy...
- PubMed ID: 25120772, Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiati...
- PubMed ID: 4002829, Antitumor activity of endogenous mFlt4 displayed on a T4 phage nanoparticle surf...
- PubMed ID: 19417736, Ren Sx, Ren Zj, Zhao My, Wang Xb, Zuo Sg, Yu F. Acta Pharmacol Sin. 2009 May;30(...
- PubMed ID: 25849455, Li J, Zeng G, Qi Y, Tang X, Zhang J, Wu Z, Liang J, Shi L, Liu H, Zhang P. Plos ...
- PubMed ID: 24339730, Dai J, Li Y, Zhou H, Chen J, Chen M, Xiao Z. Int J Biol Sci. 2013 Nov 21;9(10):1...
*More publications can be found for each product on its corresponding product page