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- Table of Contents
Estrogen receptor Antibodies
AND ESR1 ELISA kits, Estrogen receptor Proteins
Many biological assays use antibodies to detect Estrogen receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Estrogen receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Estrogen receptor antibodies...
Designing a Western blot for Estrogen receptor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ESR1 Western Blot GuideESR1 Infographic by Boster Bio
All ESR1 Products
Product
Figures
Specificity
Applications
Price
Anti-Estrogen Receptor/ESR1 Antibody Picoband®
12 Citations
Human
IHC, WB
$370
Cat # PB9192
100 μg/vial
Cat # PB9192
100 μg/vial
Anti-ER alpha ESR1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00057-2
100 μl
Cat # M00057-2
100 μl
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # P00057
100 μl
Cat # P00057
100 μl
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00057-4
100 μl/vial
Cat # M00057-4
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00057-5
20μL, 40μL, 100μL, 200μL
Cat # M00057-5
20μL, 40μL, 100μL, 200μL
Human, Mouse
ELISA, IF, IHC, WB
$380
Cat # A00057S118-3
100ul
Cat # A00057S118-3
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00057S106-1
100ul
Cat # A00057S106-1
100ul
Human
$960
Cat # LS002099
20 µg, 100 µg
Cat # LS002099
20 µg, 100 µg
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00057S104-1
100ul
Cat # A00057S104-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A00057S102
100ul
Cat # A00057S102
100ul
Human
ELISA
$540
Cat # EKC2404
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2404
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2403
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2403
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2402
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2402
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2401
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2401
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2066
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2066
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1202
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1202
1 kit, containing one 96-well plate and all necessary reagents
ESR1 Overview
Facts about Estrogen receptor.
Estrogen receptor (ESR1)
Nuclear hormone receptor. Ligand-dependent atomic transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling.
Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their various components. Mutual transrepression occurs between the estrogen receptor (ER) and NF- kappa-B in a cell-type particular manner.
Gene Information
| Human | |
|---|---|
| Gene Name: | ESR1 |
| Uniprot: | P03372 |
| Entrez: | 2099 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
ER alpha; ER; Era; ER-alpha; ESR1; ESRESRA; Estradiol receptor; estrogen receptor 1; estrogen receptor alpha delta 3*4,56,7*/819-2 isoform; estrogen receptor alpha delta 4 +49 isoform; estrogen receptor alpha delta 4*5,6,7*/654 isoform; estrogen receptor alpha; estrogen receptor; NR3A1; NR3A1DKFZp686N23123; Nuclear receptor subfamily 3 group A member 1
Molecular Weight
Mass (kDA):
66.216 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.1-q25.2 |
| Sequence: | 6; NC_000006.12 (151654148..152129619) |
Tissue Specificity
Widely expressed. Isoform 3 is not expressed in the pituitary gland.
Subcellular Localizations
[Isoform 1]: Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. A minor fraction is associated with the inner membrane.; [Isoform 3]: Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Single-pass type I membrane protein. Associated with the inner membrane via palmitoylation (Probable). At least a subset exists as a transmembrane protein with a N-terminal extracellular domain.; Nucleus. Golgi apparatus. Cell membrane. Colocalizes with ZDHHC7 and ZDHHC21 in the Golgi apparatus where most probably palmitoylation occurs.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasms
- Carcinoma
- Endometrial Polyp
- Fracture
- Osteoporosis
- Cholangiocarcinoma
- Infertility
- Cardiovascular Diseases
- Dysequilibrium Syndrome
- Carcinogenesis
Pathways
- Methylation
- Dna Methylation
- Pathogenesis
- Cell Proliferation
- Aging
- Secretion
- Localization
- Cell Cycle
- Menopause
- Ovulation
- Spermatogenesis
- Menarche
- Cell Growth
PTMs
- Methylation
- Phosphorylation
- Demethylation
- Reduction
Research Areas
- Cancer
- Cell Biology
- Cell Cycle and Replication
- Dendritic Cell Markers
- GPCR
- Neuroscience
- Signal Transduction
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ESR1
bosterbio.com/bosterbio-gene-info-cards/ESR1
References
PMID: 3754034 by Green S., et al. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A.
PMID: 3753802 by Greene G.L., et al. Sequence and expression of human estrogen receptor complementary DNA.
9 Publications of Boster Estrogen receptor Antibodies & ELISA Kits
- PubMed ID: 10.5582/bst.2015.01161, Overexpression of C35 in breast carcinomas is associated with tumor progression ...
- PubMed ID: 10.1016/S0254-6272(09)60088-1, Effect of Yikun Neiyi Wan on the Expression of Aromatase P450, COX-2, and ER Rel...
- PubMed ID: 10.1007/s11596-011-0248-z, Impact of luteinized unruptured follicles on endometrial receptivity
- PubMed ID: 29620140, Diagnostic and prognostic values of contrast-enhanced ultrasound combined with d...
- PubMed ID: 25864222, Effects of estradiol on liver estrogen receptor-? and its mRNA expression in hep...
- PubMed ID: 12133481, Fas counterattack in cholangiocarcinoma: A mechanism for immune evasion in human...
- PubMed ID: 29435117, An J, Liu T, She R, Wu Q, Tian J, Shi R, Hao W, Ren X, Yang Y, Lu Y, Yang Y, Wu ...
- PubMed ID: 20371843, Deng Yf, Chen Xx, Zhou Zl, Hou Jf. Poult Sci. 2010 May;89(5):917-23. Doi: 10.338...
- PubMed ID: 22101081, Fu Y, Zhao Z, Wu Y, Wu K, Xu X, Liu Y, Tong C. J Ethnopharmacol. 2012 Jan 6;139(...
*More publications can be found for each product on its corresponding product page