ESRRA Antibodies

AND ESRRA ELISA kits, ESRRA Proteins

Many biological assays use antibodies to detect ESRRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ESRRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ESRRA antibodies...

We validate the specificity of these antibodies to ESRRA by testing them on tissues known to express ESRRA positively and negatively. Browse below to find the ESRRA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for ESRRA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the ESRRA Western Blot Guide

ESRRA Infographic by Boster Bio

All ESRRA Products

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Specificity

Applications

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Anti-ERR alpha Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

Western blot analysis of ERR alpha expression in HeLa cell lysate

Human, Mouse, Rat

Flow Cytometry, IP, WB

$370
Cat # M03339
100 μl

Human

$628
Cat # LS002101
20 µg, 100 µg

ESRRA Overview

Facts about Steroid hormone receptor ERR1.

ESRRA 3D structure. Source: alphafold

Steroid hormone receptor ERR1 (ESRRA)

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter.

Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity.

Gene Information

Human
Gene Name:	ESRRA
Uniprot:	P11474
Entrez:	2101

Family

Belongs to:

nuclear hormone receptor family

Alternative Names

ERR alpha; ERR1; ERR1Estrogen receptor-like 1; ERRa; ESRL1; ESRL1ERR-alpha; ESRRA; estrogen-related receptor alphaERRalpha; NR3B1; NR3B1Nuclear receptor subfamily 3 group B member 1; steroid hormone receptor ERR1

Molecular Weight

Mass (kDA):
45.51 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (64305524..64316743)

Subcellular Localizations

Nucleus. Cytoplasm. Co-localizes to the cytoplasm only in presence of MAPK15.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Ovary
Osteoporosis
Ovarian Neoplasm
Carcinoma
Carcinogenesis
Neoplasms
Epithelial Ovarian Cancer
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Obesity
Cystadenocarcinoma, Serous

Malignant Neoplasm Of Breast
Uterine Cervical Neoplasm
Neuromuscular Diseases
Endometrial Neoplasms
Muscular Dystrophy, Duchenne
Malignant Tumor Of Cervix
Neoplasms, Glandular And Epithelial

Interacting Proteins

HIF1A
PIAS4
PPARGC1A

Pathways

Aging
Pathogenesis
Osteoblast Differentiation
Immune Response
Oxidative Phosphorylation
Ovulation
Chondrocyte Differentiation
Muscle Atrophy
Regeneration
Cytokine Production
Tissue Remodeling

Bone Development
Cognition
Angiogenesis
Neuromuscular Process
Excretion

PTMs

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ESRRA

References

PMID: 3267207 by Giguere V., et al. Identification of a new class of steroid hormone receptors.

PMID: 8621448 by Yang N., et al. Estrogen-related receptor, hERR1, modulates estrogen receptor- mediated response of human lactoferrin gene promoter.