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ESRRA Antibodies
AND ESRRA ELISA kits, ESRRA Proteins
Many biological assays use antibodies to detect ESRRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ESRRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ESRRA antibodies...
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ESRRA Infographic by Boster Bio
All ESRRA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M03339
100 μl
Cat # M03339
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, WB
$405
Cat # A03339-1
100ul
Cat # A03339-1
100ul
Human
IHC, WB
$523
Cat # M03339-1
100 µl
Cat # M03339-1
100 µl
Human
$628
Cat # LS002101
100 µg
Cat # LS002101
100 µg
ESRRA Overview
Facts about Steroid hormone receptor ERR1.
Steroid hormone receptor ERR1 (ESRRA)
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter.
Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | ESRRA |
| Uniprot: | P11474 |
| Entrez: | 2101 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
ERR alpha; ERR1; ERR1Estrogen receptor-like 1; ERRa; ESRL1; ESRL1ERR-alpha; ESRRA; estrogen-related receptor alphaERRalpha; NR3B1; NR3B1Nuclear receptor subfamily 3 group B member 1; steroid hormone receptor ERR1
Molecular Weight
Mass (kDA):
45.51 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.1 |
| Sequence: | 11; NC_000011.10 (64305524..64316743) |
Subcellular Localizations
Nucleus. Cytoplasm. Co-localizes to the cytoplasm only in presence of MAPK15.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Ovary
- Osteoporosis
- Ovarian Neoplasm
- Carcinoma
- Carcinogenesis
- Neoplasms
- Epithelial Ovarian Cancer
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Cystadenocarcinoma, Serous
Interacting Proteins
- HIF1A
- PIAS4
- PPARGC1A
Pathways
- Aging
- Pathogenesis
- Osteoblast Differentiation
- Immune Response
- Oxidative Phosphorylation
- Ovulation
- Chondrocyte Differentiation
- Muscle Atrophy
- Regeneration
- Cytokine Production
- Tissue Remodeling
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ESRRA
bosterbio.com/bosterbio-gene-info-cards/ESRRA
References
PMID: 3267207 by Giguere V., et al. Identification of a new class of steroid hormone receptors.
PMID: 8621448 by Yang N., et al. Estrogen-related receptor, hERR1, modulates estrogen receptor- mediated response of human lactoferrin gene promoter.