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- Table of Contents
Designing an IHC experiment for LY9? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LY9 IHC Guide1 Citations
8 Citations
1 Citations
Facts about T-lymphocyte surface antigen Ly-9.
May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to greater IL-17 secretion; the costimulatory activity demands SH2D1A (PubMed:22184727).
| Human | |
|---|---|
| Gene Name: | LY9 |
| Uniprot: | Q9HBG7 |
| Entrez: | 4063 |

| Belongs to: |
|---|
| No superfamily |

CD229 antigen; CD229; cell-surface molecule Ly-9; hly9; Ly9; lymphocyte antigen 9Cell surface molecule Ly-9; mLY9; SLAMF3; T-lymphocyte surface antigen Ly-9
Mass (kDA):
72.139 kDA

| Human | |
|---|---|
| Location: | 1q23.3 |
| Sequence: | 1; NC_000001.11 (160796112..160828256) |
Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.
Membrane; Single-pass type I membrane protein. Cell membrane.




PMID: 10970093 by Tovar V., et al. Gene structure of the mouse leukocyte cell surface molecule Ly9.
PMID: 8537117 by Sandrin M.S., et al. Isolation and characterization of cDNA clones for Humly9: the human homologue of mouse Ly9.
*More publications can be found for each product on its corresponding product page