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Product Info Summary
| SKU: | M01643-1 |
|---|---|
| Size: | 100 μl/vial |
| Reactive Species: | Mouse, Rat |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-TPH2 Antibody (Monoclonal, 35T28)
SKU/Catalog Number
M01643-1
Size
100 μl/vial
Form
Liquid
Description
Boster Bio Anti-TPH2 Antibody (Monoclonal, 35T28) catalog # M01643-1. Tested in WB, IHC, IP applications. This antibody reacts with Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TPH2 Antibody (Monoclonal, 35T28) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01643-1)
Host
Rabbit
Contents
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Monoclonal
Clone Number
35T28
Immunogen
Recombinant protein with Human THP2 aa 3-488.
Reactive Species
M01643-1 is reactive to Tph2 in Mouse, Rat
Calculated molecular weight
55.9 kDa
Background of Tph2
TPH2 protein is a key enzyme in the synthesis of serotonin in the brain. It is mainly expressed in the brain and is responsible for converting tryptophan to 5-hydroxytryptophan, a precursor of serotonin. TPH2 plays a crucial role in regulating mood, anxiety, and stress responses. Variations in the TPH2 gene have been associated with several psychiatric disorders, including depression and bipolar disorder. Additionally, TPH2 expression can be regulated by various factors, such as hormones and environmental stimuli (PMID: 22241550, PMID: 29775696, PMID: 32119710, PMID: 40204433).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01643-1 is guaranteed for IP, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 1:500-2000
Immunohistochemistry, 1:50-200
ImmunoPrecipitation, 1:50
Validation Images & Assay Conditions
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Specific Publications For Anti-TPH2 Antibody (Monoclonal, 35T28) (M01643-1)
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