Anti-Alpha A Crystallin Antibody Picoband™ (monoclonal, 8H6)

AlphaA Crystallin/CRYAA antibody

Boster Bio Anti-Alpha A Crystallin Antibody Picoband™ (monoclonal, 8H6) catalog # M01900-3. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: M01900-3
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Mouse
Application: Flow Cytometry, WB

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Product Name

Anti-Alpha A Crystallin Antibody Picoband™ (monoclonal, 8H6)

View all AlphaA Crystallin/CRYAA Antibodies

SKU/Catalog Number

M01900-3

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Alpha A Crystallin Antibody Picoband™ (monoclonal, 8H6) catalog # M01900-3. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-Alpha A Crystallin Antibody Picoband™ (monoclonal, 8H6) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01900-3)

Host

Mouse

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Monoclonal

Clone Number

8H6

Isotype

Mouse IgG2b

Immunogen

E. coli-derived human Alpha A Crystallin recombinant protein (Position: M1-S173). Human Alpha A Crystallin shares 94.8% amino acid (aa) sequence identity with both mouse and rat Alpha A Crystallin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

M01900-3 is reactive to CRYAA in Human, Mouse, Rat

Applications

M01900-3 is guaranteed for Flow Cytometry, WB Boster Guarantee

Observed Molecular Weight

20-23 kDa

Calculated molecular weight

19.909kDa

Background of AlphaA Crystallin/CRYAA

Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Flow Cytometry, 1-3 μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For CRYAA (Source: Uniprot.org, NCBI)

Gene Name

CRYAA

Full Name

Alpha-crystallin A chain

Weight

19.909kDa

Superfamily

small heat shock protein (HSP20) family

Alternative Names

AlphaA Crystallin; CRYA1; CRYA1crystallin, alpha-1; CRYAA; crystallin, alpha A; Heat shock protein beta-4; HSPB4; HSPB4alpha-crystallin A chain; human alphaA-crystallin (CRYA1), 10HspB4 CRYAA CRYA1, CTRCT9, HSPB4 crystallin alpha A alpha-crystallin A chain|crystallin, alpha-1|heat shock protein beta-4|human alphaA-crystallin (CRYA1)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CRYAA, check out the CRYAA Infographic

CRYAA infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CRYAA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01900-3

100μg

$370
M01900-3-10ug

10μg sample (liquid)

$99
M01900-3-Biotin

100 μg Biotin conjugated

$570
M01900-3-Cy3

100 μg Cy3 conjugated

$570
M01900-3-Dylight488

100 μg Dylight488 conjugated

$570
M01900-3-Dylight550

100 μg Dylight550 conjugated

$570
M01900-3-Dylight594

100 μg Dylight594 conjugated

$570
M01900-3-FITC

100 μg FITC conjugated

$570
M01900-3-HRP

100 μg HRP conjugated

$570
M01900-3-APC

100 μg APC conjugated

$670
M01900-3-PE

100 μg PE conjugated

$670
M01900-3-carrier-free

Carrier Free

$370

More conjugates/formats

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M01900-3
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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