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- Table of Contents
Alpha-crystallin A chain Antibodies
AND CRYAA ELISA kits, Alpha-crystallin A chain Proteins
Many biological assays use antibodies to detect Alpha-crystallin A chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-crystallin A chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-crystallin A chain antibodies...
Designing a Western blot for Alpha-crystallin A chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CRYAA Western Blot GuideCRYAA Infographic by Boster Bio
All CRYAA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # PB9940
100 μg/vial
Cat # PB9940
100 μg/vial
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # M01900-2
100 μg/vial
Cat # M01900-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M01900-3
100 μg/vial
Cat # M01900-3
100 μg/vial
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M01900-1
100 µl
Cat # M01900-1
100 µl
Human, Mouse, Rat, Zebrafish
IF, ICC, WB
$405
Cat # A01900
100ul
Cat # A01900
100ul
Human
$628
Cat # LS001409
20 µg, 100 µg
Cat # LS001409
20 µg, 100 µg
CRYAA Overview
Facts about Alpha-crystallin A chain.
Alpha-crystallin A chain (CRYAA)
Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of different proteins under a broad range of stress conditions.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CRYAA |
| Uniprot: | P02489 |
| Entrez: | 1409 |
Family
| Belongs to: |
|---|
| small heat shock protein (HSP20) family |
Alternative Names
AlphaA Crystallin; CRYA1; CRYA1crystallin, alpha-1; CRYAA; crystallin, alpha A; Heat shock protein beta-4; HSPB4; HSPB4alpha-crystallin A chain; human alphaA-crystallin (CRYA1), 10HspB4
Molecular Weight
Mass (kDA):
19.909 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.3 |
| Sequence: | 21; NC_000021.9 (43169008..43172810) |
Tissue Specificity
Expressed in eye lens.
Subcellular Localizations
Cytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Diseases
- Cataract
- Corneal Diseases
- Nuclear Cataract
- Eye Abnormalities
- Blind Vision
- Disorder Of Eye
- Senile Cataract
- Lens Diseases
- Visual Impairment
- Congenital Lamellar Cataract
- Congenital Coloboma Of Iris
Interacting Proteins
- CRYAB
- CRYGC
- GORASP2
- SDCBP
- SPG21
- WDYHV1
Pathways
- Pathogenesis
- Localization
- Cell Differentiation
- Eye Development
- Oncogenesis
- Cell Death
- Angiogenesis
- Cell Adhesion
- Transport
- Cell Migration
- Aging
- Neurogenesis
- Virulence
PTMs
- Phosphorylation
- Demethylation
Research Areas
- Membrane Trafficking and Chaperones
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRYAA
bosterbio.com/bosterbio-gene-info-cards/CRYAA
References
PMID: 817940 by de Jong W.W., et al. The amino acid sequence of the A chain of human alpha-crystallin.
PMID: 8587135 by Jaworski C.J.; A reassessment of mammalian alpha A-crystallin sequences using DNA sequencing: implications for anthropoid affinities of tarsier.