Anti-AMHR2 Antibody Picoband™

MIS RII/AMHR2 antibody

Boster Bio Anti-AMHR2 Antibody Picoband™ catalog # PB9984. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PB9984
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IF, IHC, ICC, WB

Product Name

Anti-AMHR2 Antibody Picoband™

View all MIS RII/AMHR2 Antibodies

SKU/Catalog Number

PB9984

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-AMHR2 Antibody Picoband™ catalog # PB9984. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-AMHR2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9984)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human AMHR2, different from the related mouse and rat sequences by three amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9984 is reactive to AMHR2 in Human, Mouse, Rat

Applications

PB9984 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

65 kDa

Calculated molecular weight

62.75kDa

Background of MIS RII/AMHR2

AMHR2 is the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry, 1-3 μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For AMHR2 (Source: Uniprot.org, NCBI)

Gene Name

AMHR2

Full Name

Anti-Muellerian hormone type-2 receptor

Weight

62.75kDa

Superfamily

protein kinase superfamily

Alternative Names

AMH type II receptor; AMHR2; AMHREC 2.7.11.30; AMHRII; C14; MIS RII; MISR2; MISRII; MISRIIMIS type II receptor; MRII; Muellerian hormone type II receptor; Muellerian hormone type-2 receptor; Mullerian hormone receptor, type II; Mullerian inhibiting substance type II receptor AMHR2 AMHR, MISR2, MISRII, MRII anti-Mullerian hormone receptor type 2 anti-Muellerian hormone type-2 receptor|AMH type II receptor|MIS type II receptor|Muellerian inhibiting substance type II receptor|Mullerian inhibiting substance type II receptor|anti-Muellerian hormone type II receptor|anti-Mullerian hormone receptor, type II

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on AMHR2, check out the AMHR2 Infographic

AMHR2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for AMHR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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6 Customer Q&As for Anti-AMHR2 Antibody Picoband™

Question

Thanks for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for testis using anti-AMHR2 antibody PB9984. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2019-07-12

Answer

We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-07-12

Question

My question regarding product PB9984, anti-AMHR2 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Verified Customer

Verified customer

Asked: 2019-06-24

Answer

We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PB9984 anti-AMHR2 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2019-06-24

Question

Does anti-AMHR2 antibody PB9984 work on horse WB with testis?

Verified Customer

Verified customer

Asked: 2019-05-27

Answer

Our lab technicians have not tested anti-AMHR2 antibody PB9984 on horse. You can run a BLAST between horse and the immunogen sequence of anti-AMHR2 antibody PB9984 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated horse samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in horse testis in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-05-27

Question

Here is the WB image, lot number and protocol we used for testis using anti-AMHR2 antibody PB9984. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2018-07-16

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2018-07-16

Question

My lab would like to test anti-AMHR2 antibody PB9984 on human testis for research purposes, then I may be interested in using anti-AMHR2 antibody PB9984 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2017-09-13

Answer

The products we sell, including anti-AMHR2 antibody PB9984, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2017-09-13

Question

We are currently using anti-AMHR2 antibody PB9984 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, rat. Is it possible that the antibody can work on pig tissues as well?

G. Jones

Verified customer

Asked: 2014-08-14

Answer

The anti-AMHR2 antibody (PB9984) has not been tested for cross reactivity specifically with pig tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2014-08-14

Size

Conjugation

Total: $370

SKU:PB9984

In stock, 1 left.

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PB9984
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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