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- Table of Contents
Androgen receptor Antibodies
AND AR ELISA kits, Androgen receptor Proteins
Many biological assays use antibodies to detect Androgen receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Androgen receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Androgen receptor antibodies...
Designing a Western blot for Androgen receptor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AR Western Blot GuideDesigning an IHC experiment for Androgen receptor? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AR IHC GuideAR Infographic by Boster Bio
All AR Products
Product
Figures
Specificity
Applications
Price
$95
Cat # AR0135-02
0.22um, 9cm × 10 cm; 20 sheets
Cat # AR0135-02
0.22um, 9cm × 10 cm; 20 sheets
$90
Cat # AR0135-04
0.45µm, 9cm × 10 cm; 20 sheets
Cat # AR0135-04
0.45µm, 9cm × 10 cm; 20 sheets
AR Overview
Facts about Androgen receptor.
Androgen receptor (AR)
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins.
Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Gene Information
| Human | |
|---|---|
| Gene Name: | AR |
| Uniprot: | P10275 |
| Entrez: | 367 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
AIS; Androgen R; androgen receptor; AndrogenR; AR; DHTR; DHTRTFM; Dihydrotestosterone receptorHYSP1; HUMARA; NR3C4; NR3C4KD; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; SMAX1SBMA; spinal and bulbar muscular atrophy
Molecular Weight
Mass (kDA):
99.188 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq12 |
| Sequence: | X; NC_000023.11 (67544021..67730619) |
Tissue Specificity
Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).
Subcellular Localizations
Nucleus. Cytoplasm. Detected at the promoter of target genes (PubMed:25091737). Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Neoplasms
- Carcinoma
- Mammary Neoplasms
- Rhinorrhea
- Malignant Neoplasm Of Breast
- Allergic Rhinitis (disorder)
- Regurgitation
- Inflammation
- Aortic Valve Insufficiency
- Hyperplasia
Pathways
- Cell Proliferation
- Localization
- Acrosome Reaction
- Cell Growth
- Pathogenesis
- Secretion
- Cell Cycle
- Transport
- Fertilization
- Cell Death
- Spermatogenesis
- Methylation
- Aging
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Oxidation
- Acetylation
- Reduction
- Ubiquitination
- Glycosylation
- Sumoylation
- Carboxylation
Research Areas
- Breast Cancer
- Cancer
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AR
bosterbio.com/bosterbio-gene-info-cards/AR
References
PMID: 3216866 by Lubahn D.B., et al. The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate.
PMID: 3174628 by Chang C., et al. Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.
542 Publications of Boster Androgen receptor Antibodies & ELISA Kits
- PubMed ID: 38833761, Oyster mantle-derived exosomes alleviate osteoporosis by regulating bone homeost...
- PubMed ID: PMID:33527029, Ozonated autohemotherapy elevates PPAR-γ expression in CD4+ T cells and serum H...
- PubMed ID: PMID:31934207, The functional role of RNF113A in cervical carcinogenesis
- PubMed ID: PMID:25674205, The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclo...
- PubMed ID: PMID:24427322, Role of PDGFs/PDGFRs signaling pathway in myocardial fibrosis of DOCA/salt hyper...
- PubMed ID: 10.7150/thno.29101, Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Target...
- PubMed ID: 10.7150/jca.56640, SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration o...
- PubMed ID: 10.7150/ijms.51176, Estrogen receptor α/prolactin receptor bilateral crosstalk promotes bromocripti...
- PubMed ID: 10.7150/ijbs.41940, Ozone Therapy Attenuates NF-κB-Mediated Local Inflammatory Response and Activat...
- PubMed ID: 10.5713/ajas.15.0711, Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Al...
- PubMed ID: 10.4142/jvs.2020.21.e50, Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TL...
- PubMed ID: 10.4103/aja.aja_41_19, Establishing a nonlethal and efficient mouse model of male gonadotoxicity by int...
- PubMed ID: 10.4103/1673-5374.180750, Anti-inflammatory properties of lipoxin A4 protect against diabetes mellitus com...
- PubMed ID: 10.3892/or.2016.4989, Decreased LIPF expression is correlated with DGKA and predicts poor outcome of g...
- PubMed ID: 10.3892/ol.2021.12672, Expression and prognostic value of E2F3 transcription factor in non‑small cell...
- PubMed ID: 10.3892/ol.2021.12550, PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV‑negative head and neck ...
- PubMed ID: 10.3892/ol.2020.11796, Downregulation of microRNA‑126 is inversely correlated with insulin receptor s...
- PubMed ID: 10.3892/ol.2020.11349, Flotillin‑2 predicts poor prognosis and promotes tumor invasion in intrahepati...
- PubMed ID: 10.3892/ol.2019.11128, Transcriptome changes induced by RUNX3 in cervical cancer cells in vitro
- PubMed ID: 10.3892/ol.2019.10109, Overexpression of malignant brain tumor domain containing protein 1 predicts a p...
- PubMed ID: 10.3892/ol.2018.9490, High levels of glioma tumor suppressor candidate region gene 1 predicts a poor p...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page