|Validated Species:||Chicken, Rat|
Data & Images
|Product Name||Anti-Calmodulin Antibody (Monoclonal, 6D4)|
|Description||Mouse IgG monoclonal antibody for Calmodulin, calmodulin 1; calmodulin 2; calmodulin 3 (CALM1; CALM2; CALM3) detection. Tested with WB in chicken;rat. No cross reactivity with other proteins.|
|Cite This Product||Anti-Calmodulin Antibody (Monoclonal, 6D4) 6D4 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1010)|
|Replacement Item||This antibody may replace the following items: sc-137079|sc-17018-R|sc-17019|sc-17019-R|sc-17022-R|sc-17023-R|sc-1989|sc-23760-R|sc-23761-R|sc-34082|sc-5537 from Santa Cruz Biotechnology.|
|Validated Species||Chicken, Rat|
*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.
*Our Boster Guarantee covers the use of this product in the above tested applications.
**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.
|Recommended Detection Systems||Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2018!
|Immunogen||Preparation of purified calmodulin from Dictyostelium discoideum conjugated to KLH.|
|Cross Reactivity||No cross reactivity with other proteins|
|Contents||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Concentration||Add 1ml of PBS buffer will yield a concentration of 100ug/ml.|
|Storage||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
Protein Target Info (Source: Uniprot.org)
You can check the tissue specificity below for information on selecting positive and negative control.
|Molecular Weight||16838 MW|
|Protein Function||Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). .|
|Sequence Similarities||Belongs to the calmodulin family.|
|Subcellular Localization||Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules. .|
|Alternative Names||Calmodulin;CaM;Calm1;Calm, Cam, Cam1;Calm2;Cam2, Camb;Calm3;Cam3, Camc;|
|Research Areas||signal transduction|signaling pathway|calcium signaling|calmodulin pathway|cardiovascular|atherosclerosis|apoptosis|heart|cardiac metabolism|cancer|cancer metabolism|metabolic signaling pathway|metabolism of carbohydrates|pathways and processes|metabolic signaling pathways|carbohydrate metabolism|types of disease|heart disease||