Anti-CRSP130 MED23 Antibody

MED23 antibody

Boster Bio Anti-CRSP130 MED23 Antibody catalog # A03859-2. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A03859-2
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC, WB

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Product Name

Anti-CRSP130 MED23 Antibody

View all MED23 Antibodies

SKU/Catalog Number

A03859-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CRSP130 MED23 Antibody catalog # A03859-2. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CRSP130 MED23 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03859-2)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CRSP130

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03859-2 is reactive to MED23 in Human, Mouse, Rat

Applications

A03859-2 is guaranteed for ELISA, IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

156.474kDa

Background of MED23

Required for transcriptional activation subsequent to the assembly of the preinitiation complex By similarity. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.

Wiemann S., Genome Res. 11:422-435(2001).
Mungall A.J., Nature 425:805-811(2003).
Akoulitchev S., Nature 407:102-106(2000).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Validation Images & Assay Conditions

Gene/Protein Information For MED23 (Source: Uniprot.org, NCBI)

Gene Name

MED23

Full Name

Mediator of RNA polymerase II transcription subunit 23

Weight

156.474kDa

Superfamily

Mediator complex subunit 23 family

Alternative Names

130 kDa transcriptional co-activator; 133 kDa transcriptional co-activator; CRSP130; DRIP130DKFZp434H0117; mediator complex subunit 23CRSP133; Protein sur-2 homolog; subunit 3, 130kDa; Transcriptional coactivator CRSP130; Vitamin D3 receptor-interacting protein complex 130 kDa component MED23 ARC130, CRSP130, CRSP133, CRSP3, DRIP130, MRT18, SUR-2, SUR2 mediator complex subunit 23 mediator of RNA polymerase II transcription subunit 23|130 kDa transcriptional co-activator|133 kDa transcriptional co-activator|activator-recruited cofactor 130 kDa component|cofactor required for Sp1 transcriptional activation subunit 3|mental retardation, non-syndromic, autosomal recessive, 18|vitamin D3 receptor interacting protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MED23, check out the MED23 Infographic

MED23 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MED23: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03859-2-100ul

100ul

$380

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