Product Info Summary
SKU: | A03889-1 |
---|---|
Size: | 100μl |
Reactive Species: | Human, Monkey, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Cyclin A Antibody
SKU/Catalog Number
A03889-1
Size
100μl
Form
Liquid
Description
Boster Bio Anti-Cyclin A Antibody catalog # A03889-1. Tested in WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cyclin A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03889-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human Cyclin A. at AA rangle: 190-270
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03889-1 is reactive to CCNA1 in Human, Monkey, Mouse, Rat
Applications
A03889-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
52.358kDa
Background of Cyclin A1
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Chong J.A.et.al. (1995)Cell 80:949-957
Schoenherr C.J.et.al.(1995)Science 267:1360-1363
Scholl T.et.al.(1996)J. Immunol. 156:1448-1457
Lunyak V.V.et.al. (2002)Science 298:1747-1752
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Western Blot (WB) analysis of COS7 cells using Cyclin A Polyclonal antibody.
Click image to see more details
Western Blot (WB) analysis of specific cells using Cyclin A Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For CCNA1 (Source: Uniprot.org, NCBI)
Gene Name
CCNA1
Full Name
Cyclin-A1
Weight
52.358kDa
Superfamily
cyclin family
Alternative Names
CCNA1; Cyclin A1; cyclin-A1 CCNA1 CT146 cyclin A1 cyclin-A1|testicular tissue protein Li 34
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CCNA1, check out the CCNA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CCNA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cyclin A Antibody (A03889-1)
Hello CJ!
A03889-1 has been cited in 5 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
All-trans-retinoic acid inhibits mink hair follicle growth via inhibiting proliferation and inducing apoptosis of dermal papilla cells through TGF-β2/Smad2/3 pathway
Chaowei Hu,Kun Zuo,Kuibao Li,Yuanfeng Gao,Mulei Chen,Roumu Hu,Ye Liu,Hongjie Chi,Hongjiang Wang,Yanwen Qin,Xiaoyan Liu,Jiuchang Zhong,Jun Cai,Xinchun Yang,Jing Li, "p38/JNK Is Required for the Proliferation and Phenotype Changes of Vascular Smooth Muscle
Species: Rat,Human
A03889-1 usage in article: APP:WB, SAMPLE:VSMCS, DILUTION:NA
Nan W,Li G,Si H,Lou Y,Wang D,Guo R,Zhang H.All-trans-retinoic acid inhibits mink hair follicle growth via inhibiting proliferation and inducing apoptosis of dermal papilla cells through TGF-β2/Smad2/3 pathway. Acta Histochem. 2020 Oct;122(7):151603.doi: 1
Species: American mink
A03889-1 usage in article: APP:WB, SAMPLE:HAIR FOLLICLES AND DPCS, DILUTION:1:300
Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2
Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury
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