Product Info Summary
SKU: | A01110-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Dopamine beta-hydroxylase DBH Antibody
View all Dopamine beta-Hydroxylase Antibodies
SKU/Catalog Number
A01110-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Dopamine beta-hydroxylase DBH Antibody catalog # A01110-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Dopamine beta-hydroxylase DBH Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01110-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Pdcd-4 around the phosphorylation site of S67.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01110-1 is reactive to DBH in Human, Mouse, Rat
Applications
A01110-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
69.065kDa
Background of Dopamine beta-Hydroxylase
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For DBH (Source: Uniprot.org, NCBI)
Gene Name
DBH
Full Name
Dopamine beta-hydroxylase
Weight
69.065kDa
Superfamily
copper type II ascorbate-dependent monooxygenase family
Alternative Names
DBH; DBM; dopamine beta-hydroxylase (dopamine beta-monooxygenase); Dopamine betaHydroxylase; Dopamine beta-Hydroxylase; Dopamine beta-monooxygenase; DOPBHY; EC 1.14.17.1 DBH DBM, ORTHYP1 dopamine beta-hydroxylase dopamine beta-hydroxylase|dopamine beta-hydroxylase (dopamine beta-monooxygenase)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DBH, check out the DBH Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DBH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Dopamine beta-hydroxylase DBH Antibody (A01110-1)
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No publications found for A01110-1
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