Anti-DR5/TNFRSF10B Antibody Picoband™

TRAILR2/TNFRSF10B antibody

Boster Bio Anti-DR5/TNFRSF10B Antibody Picoband™ catalog # A00410. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: A00410
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IHC, WB

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Product Name

Anti-DR5/TNFRSF10B Antibody Picoband™

View all TRAILR2/TNFRSF10B Antibodies

SKU/Catalog Number

A00410

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-DR5/TNFRSF10B Antibody Picoband™ catalog # A00410. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DR5/TNFRSF10B Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00410)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human DR5 recombinant protein (Position: K233-S440). Human DR5 shares 48.4% amino acid (aa) sequence identity with mouse DR5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

A00410 is reactive to TNFRSF10B in Human, Mouse, Rat

Applications

A00410 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee

Observed Molecular Weight

60 kDa

Calculated molecular weight

47.878kDa

Background of TRAILR2/TNFRSF10B

TNFRSF10B (Tumor necrosis factor receptor superfamily, member 10b) is a human gene. It is also known as DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Mice have a homologous gene, tnfrsf10b that has been essential in the elucidation of the function of this gene in humans. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.By analysis of radiation hybrid panels, this gene is mapped to chromosome 8p22-p21. Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested, with the highest levels of expression in peripheral blood lymphocytes, spleen, and ovary.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For TNFRSF10B (Source: Uniprot.org, NCBI)

Gene Name

TNFRSF10B

Full Name

Tumor necrosis factor receptor superfamily member 10B

Weight

47.878kDa

Alternative Names

CD262 antigen; CD262; death domain containing receptor for TRAIL/Apo-2L; Death receptor 5; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; KILLERapoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRAIL-R2apoptosis inducing receptor TRAIL-R2; TRAILR2cytotoxic TRAIL receptor-2; TRICK2; TRICK2A; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; ZTNFR9 TNFRSF10B CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 TNF receptor superfamily member 10b tumor necrosis factor receptor superfamily member 10B|Fas-like protein|TNF-related apoptosis-inducing ligand receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|death receptor 5|p53-regulated DNA damage-inducible cell death receptor(killer)|tumor necrosis factor receptor superfamily, member 10b|tumor necrosis factor receptor-like protein ZTNFR9

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TNFRSF10B, check out the TNFRSF10B Infographic

TNFRSF10B infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TNFRSF10B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00410 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Yoo I,Kye YC,Han J,Kim M,Lee S,Jung W,Hong M,Park TS,Yun CH,Ka H.Uterine epithelial expression of the tumor necrosis factor superfamily: a strategy for immune privilege during pregnancy in a true epitheliochorial placentation species.Biol Reprod.2020 Apr
Species: Pig
A00410 usage in article: APP:IHC, SAMPLE:UTERINE TISSUE, DILUTION:NA

Liu N, Zuo C, Wang X, Chen T, Yang D, Wang J, Zhu H. Oncotarget. 2014 Jul 15;5(13):4959-71. Mir-942 Decreases Trail-Induced Apoptosis Through Isg12A Downregulation And Is Regulated By Akt.

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Order DetailsPrice
A00410

100μg

$370
A00410-10ug

10μg sample (liquid)

$99
A00410-Biotin

100 μg Biotin conjugated

$570
A00410-Cy3

100 μg Cy3 conjugated

$570
A00410-Dylight488

100 μg Dylight488 conjugated

$570
A00410-Dylight550

100 μg Dylight550 conjugated

$570
A00410-Dylight594

100 μg Dylight594 conjugated

$570
A00410-FITC

100 μg FITC conjugated

$570
A00410-HRP

100 μg HRP conjugated

$570
A00410-APC

100 μg APC conjugated

$670
A00410-PE

100 μg PE conjugated

$670
A00410-carrier-free

Carrier Free

$370

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$370.00

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