Anti-Interferon regulatory factor 5 IRF5 Antibody Picoband®

Product Name

Anti-Interferon regulatory factor 5 IRF5 Antibody Picoband®

View all IRF5 Antibodies

SKU/Catalog Number

PA2208

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Interferon regulatory factor 5 IRF5 Antibody catalog # PA2208. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Interferon regulatory factor 5 IRF5 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2208)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human IRF5, identical to the related rat sequence, and different from the related mouse sequence by two amino acids.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2208 is reactive to IRF5 in Human, Mouse, Rat

Observed Molecular Weight

53 kDa

Calculated molecular weight

56.0 kDa

Background of IRF5

Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2208 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Positive Control

WB: Human Placenta Tissue, Rat Thymus Tissue, Rat Kidney Tissue, Rat Ovary Tissue,

Validation Images & Assay Conditions

See full target information IRF5

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