Product Info Summary
SKU: | A06890 |
---|---|
Size: | 100ul |
Reactive Species: | Mouse, Rat |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-Dynamin-3 DNM3 Antibody
SKU/Catalog Number
A06890
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Dynamin-3 DNM3 Antibody catalog # A06890. Tested in WB,ICC/IF applications. This antibody reacts with Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Dynamin-3 DNM3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06890)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Rag A/B
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06890 is reactive to DNM3 in Mouse, Rat
Applications
A06890 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
97.746kDa
Background of Dynamin 3
Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Ota T., Nat. Genet. 36:40-45(2004).
Scherer S.E., Nature 440:346-351(2006).
Channavajhala P.L., J. Biol. Chem. 278:47089-47097(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Dynamin-3 DNM3 Antibody A06890
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For DNM3 (Source: Uniprot.org, NCBI)
Gene Name
DNM3
Full Name
Dynamin-3
Weight
97.746kDa
Superfamily
TRAFAC class dynamin-like GTPase superfamily
Alternative Names
Dyna III; dynamin 3; dynamin family member; dynamin-3; EC 3.6.5.5; MGC70433; T-dynamin; testicular DNM3 Dyna III dynamin 3 dynamin-3|T-dynamin|dynamin family member|dynamin, testicular
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DNM3, check out the DNM3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DNM3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Dynamin-3 DNM3 Antibody (A06890)
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No publications found for A06890
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