|Ig Isotype||Mouse IgG1|
|Product Name||Anti-Elastin Antibody (Monoclonal, BA-4)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for Elastin, elastin (ELN ) detection. Tested with IHC-P in Human; bovine. No cross reactivity with otherproteins.|
|Cite This Product||Anti-Elastin Antibody (Monoclonal, BA-4) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1038)|
Assay Dilutions Overview
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
Protein Target Info (Source: Uniprot.org)
|Tissue Specificity||Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin. .|
|Subcellular Localization||Secreted, extracellular space, extracellular matrix . Extracellular matrix of elastic fibers. .|
|Molecular Weight||68469 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity). .|
|Background||Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.|
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