FANCA Antibodies

AND FANCA ELISA kits, FANCA Proteins

Many biological assays use antibodies to detect FANCA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FANCA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FANCA antibodies...

We validate the specificity of these antibodies to FANCA by testing them on tissues known to express FANCA positively and negatively. Browse below to find the FANCA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for FANCA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the FANCA Western Blot Guide

FANCA Infographic by Boster Bio

All FANCA Products

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Product

Figures

Specificity

Applications

Price

Anti-Fanca/FAA Antibody Picoband®

Western blot analysis of Fanca/FAA using anti-Fanca/FAA antibody (A03662-2)

Flow Cytometry analysis of ANA-1 cells using anti-Fanca/FAA antibody (A03662-2)

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03662-2
100 μg/vial

Anti-FANCA Rabbit Monoclonal Antibody

Western blot analysis of FANCA expression in A431 cell lysate

Human

IP, WB

$370
Cat # M03662
100 μl/vial

FANCA (NM_001018112) Human Over-expression Lysate

Human

$628
Cat # LS002175
20 µg, 100 µg

FANCA Overview

Facts about Fanconi anemia group A protein.

FANCA 3D structure. Source: alphafold

Fanconi anemia group A protein (FANCA)

DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link fix and in the maintenance of normal chromosome stability.

Gene Information

Human
Gene Name:	FANCA
Uniprot:	O15360
Entrez:	2175

Family

Belongs to:

No superfamily

Alternative Names

FA; FA1; FAA; FAAMGC75158; FACA; FACAFanconi anemia group A protein; FAH; FA-H; FANCA; FANCH; Fanconi anemia, complementation group A; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA

Molecular Weight

Mass (kDA):
162.775 kDA

Genomic Context


Human

Location:	16q24.3
Sequence:	16; NC_000016.10 (89737549..89816647, complement)

Subcellular Localizations

Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.

Diseases

Anemia
Fanconi Anemia
Malignant Neoplasms
Pancytopenia
Congenital Abnormality
Neoplasms
Hereditary Diseases
Leukemia
Malignant Neoplasm Of Breast
Chromosome Breakage
Myeloid Leukemia
Leukemia, Myelocytic, Acute
Aplastic Anemia

Carcinoma
Malignant Squamous Cell Neoplasm
Genomic Instability
Instabilities, Chromosomal
Cytogenetic Abnormality
Mammary Neoplasms
Embryonic Mosaic

Interacting Proteins

FAAP100
FANCF
FANCG
GRB2

Pathways

Hypersensitivity
Dna Repair
Localization
Cell Cycle
Pathogenesis
Cell Death
Chromosome Breakage
Dna Replication
Nuclear Import
Senescence
Nuclear Export
Gene Conversion
Interstrand Cross-link Repair

S Phase
Cell Cycle Checkpoint
Mitosis
Methylation
Cell Growth
Translesion Synthesis
Transport

PTMs

Phosphorylation
Ubiquitination
Methylation

Cleavage
Demethylation
Reduction

Research Areas

Cancer
DNA Repair
Genes Sensitive to DNA Damaging Agents

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FANCA

References

PMID: 8896563 by Lo Ten Foe J.R., et al. Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA.

PMID: 9169126 by Ianzano L., et al. The genomic organization of the Fanconi anemia group A (FAA) gene.