Product Info Summary
SKU: | A02615 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Fos-related antigen 2 FOSL2 Antibody
SKU/Catalog Number
A02615
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Fos-related antigen 2 FOSL2 Antibody catalog # A02615. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Fos-related antigen 2 FOSL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02615)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Y185.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02615 is reactive to FOSL2 in Human, Mouse, Rat
Applications
A02615 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
35.193kDa
Background of FRA2
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:100-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For FOSL2 (Source: Uniprot.org, NCBI)
Gene Name
FOSL2
Full Name
Fos-related antigen 2
Weight
35.193kDa
Superfamily
bZIP family
Alternative Names
FOS-like antigen 2; fos-related antigen 2; FRA-2; FRA2FLJ23306 FOSL2 FRA2 FOS like 2, AP-1 transcription factor subunit fos-related antigen 2|FOS like 2, AP-1 trancription factor subunit|FOS like antigen 2|FRA-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FOSL2, check out the FOSL2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FOSL2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Fos-related antigen 2 FOSL2 Antibody (A02615)
Hello CJ!
A02615 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Bi,F.,Chen,C.,Fu,J.,Yu,L.,& Geng,J.(2021).Inhibiting proliferation and metastasis of osteosarcoma cells by downregulation of long non‑coding RNA colon cancer‑associated transcript 2 targeting microRNA‑143.Oncology Letters,21,265.https://doi.org/10.3892/ol
Species: Human
A02615 usage in article: APP:WB, SAMPLE:MG63 CELL AND U2OS CELL, DILUTION:1:1000
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