Anti-FRMPD1 Antibody

FRMPD1 antibody

Boster Bio Anti-FRMPD1 Antibody (Catalog # A10887). Tested in ELISA, WB, IF applications. This antibody reacts with Human.

Product Info Summary

SKU: A10887
Size: 0.1 mg
Reactive Species: Human
Host: Rabbit
Application: ELISA, IF, WB

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Product Name

Anti-FRMPD1 Antibody

View all FRMPD1 Antibodies

SKU/Catalog Number

A10887

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-FRMPD1 Antibody (Catalog # A10887). Tested in ELISA, WB, IF applications. This antibody reacts with Human.

Storage & Handling

FRMPD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-FRMPD1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10887)

Host

Rabbit

Contents

FRMPD1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

FRMPD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human FRMPD1. The immunogen is located within amino acids 1330 - 1380 of FRMPD1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A10887 is reactive to FRMPD1 in Human

Applications

A10887 is guaranteed for ELISA, IF, WB Boster Guarantee

Background of FRMPD1

The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50% and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

FRMPD1 antibody can be used for detection of FRMPD1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunoflourescence starting at 20 μg/mL. For immunofluorescence start at 5 μg/mL. Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For FRMPD1 (Source: Uniprot.org, NCBI)

Uniprot ID

Q5SYB0

Gene ID

22844

Gene Name

FRMPD1

Full Name

FERM and PDZ domain-containing protein 1

Weight

173.437kDa

Alternative Names

FERM and PDZ domain containing 1; FERM and PDZ domain-containing protein 1; FRMD2KIAA0967FERM domain-containing protein 2; MGC138833 FRMPD1 FRMD2 FERM and PDZ domain containing 1 FERM and PDZ domain-containing protein 1|FERM domain-containing protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on FRMPD1, check out the FRMPD1 Infographic

FRMPD1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for FRMPD1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $404

SKU:A10887

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Ships directly to USA and Canada. For other regions, visit our distributors page

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A10887
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$404.00

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