Product Info Summary
| SKU: | M03913 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | FACS |
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Product info
Product Name
Anti-hCD6 Antibody (Monoclonal, SPV14)
SKU/Catalog Number
M03913
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-hCD6 Antibody (Monoclonal, SPV14) (Catalog# M03913). Tested in FACS application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-hCD6 Antibody (Monoclonal, SPV14) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03913)
Host
Mouse
Contents
100 µg in 200 µl PBS containing 0.05% stabilizing protein and 0.05% sodium azide
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Monoclonal
Clone Number
SPV14
Isotype
IgG2a Kappa
Immunogen
CD8+ cytotoxic T-cells
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M03913 is reactive to CD6 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
71.8 kDa
Background of CD6
This monoclonal antibody recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M03913 is guaranteed for FACS Boster Guarantee
Recommend Dilution
FACS: 0.5-1 µg/10^6 cells
Validation Images & Assay Conditions
Click image to see more details
Cell Surface flow analysis of hCD6 in PBMC (Lymphocyte gated) using 0.5 &mu
Specific Publications For Anti-hCD6 Antibody (Monoclonal, SPV14) (M03913)
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Customer Q&As
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1 Customer Q&As for Anti-hCD6 Antibody (Monoclonal, SPV14)
Question
We are currently using anti-hCD6 antibody (Monoclonal, SPV14) M03913 for human tissue, and we are happy with the Flow Cytometry results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on dog tissues as well?
M. Lewis
Verified customer
Asked: 2017-10-31
Answer
The anti-hCD6 antibody (Monoclonal, SPV14) (M03913) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2017-10-31

