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- Table of Contents
CD6 Antibodies
AND CD6 ELISA kits, CD6 Proteins
Many biological assays use antibodies to detect CD6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD6 antibodies...
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CD6 Infographic by Boster Bio
All CD6 Products
Product
Figures
Specificity
Applications
Price
Anti-Macrosialin CD68 Antibody Picoband®
194 Citations
Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # PA1518
100 μg/vial
Cat # PA1518
100 μg/vial
Human
ELISA
$499
Cat # EK0501
96 wells/kit, with removable strips.
Cat # EK0501
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0506
96 wells/kit, with removable strips.
Cat # EK0506
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0505
96 wells/kit, with removable strips.
Cat # EK0505
96 wells/kit, with removable strips.
Anti-PAR2 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01081
100 μl/vial
Cat # M01081
100 μl/vial
Human
ELISA
$500
Cat # EZ0505
5 plates/kit
Cat # EZ0505
5 plates/kit
Human soluble CD6 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1221
96 wells/kit, with removable strips.
Cat # EK1221
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0505
96 wells/kit, with removable strips.
Cat # FEK0505
96 wells/kit, with removable strips.
Human CEACAM1/Cd66A ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1361
96 wells/kit, with removable strips.
Cat # EK1361
96 wells/kit, with removable strips.
Anti-CD69 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00529-2
100 μg/vial
Cat # A00529-2
100 μg/vial
Human
ELISA
$500
Cat # EZ0501
5 plates/kit
Cat # EZ0501
5 plates/kit
Human
ELISA
$500
Cat # EZ0904
For 5 plates, 96 wells each
Cat # EZ0904
For 5 plates, 96 wells each
Mouse
ELISA
$499
Cat # FEK0506
96 wells/kit, with removable strips.
Cat # FEK0506
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1221
96 wells/kit, with removable strips.
Cat # FEK1221
96 wells/kit, with removable strips.
Anti-CD62P/Selp Antibody Picoband®
3 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01241-1
100 μg/vial
Cat # A01241-1
100 μg/vial
Mouse
ELISA
$500
Cat # EZ2053
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ2053
For 5 plates, 96 wells each, reagents only, plates are not included
Mouse
ELISA
$500
Cat # EZ0506
5 plates/kit
Cat # EZ0506
5 plates/kit
Mouse
ELISA
$499
Cat # EK1287
96 wells/kit, with removable strips.
Cat # EK1287
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK1287
96 wells/kit, with removable strips.
Cat # FEK1287
96 wells/kit, with removable strips.
Human
IF, IHC, ICC, WB
$370
Cat # M00356-1
100 μl
Cat # M00356-1
100 μl
Anti-CD68/Sr D1 Rabbit Monoclonal Antibody
2 Citations
Human, Mouse, Rat
WB
$370
Cat # M00602-1
100 μl
Cat # M00602-1
100 μl
Anti-CEACAM5 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00356
100 μg/vial
Cat # A00356
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01242-3
100 μg/vial
Cat # A01242-3
100 μg/vial
Anti-E-selectin/CD62E/SELE antibody
8 Citations
Human
ELISA, Flow Cytometry, IHC
$370
Cat # A04224-1
100 μl/vial
Cat # A04224-1
100 μl/vial
Anti-CD62L/SELL Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # PB9389
100 μg/vial
Cat # PB9389
100 μg/vial
Human
ELISA
$500
Cat # EZ0503
For 5 plates, 96 wells each
Cat # EZ0503
For 5 plates, 96 wells each
Anti-Macrosialin CD68 Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IF, IHC
$380
Cat # M00602-2
100ul
Cat # M00602-2
100ul
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00602-4
20μL, 40μL, 100μL, 200μL
Cat # M00602-4
20μL, 40μL, 100μL, 200μL
Human
ELISA, IHC, WB
$449
Cat # M00356-3
100uL
Cat # M00356-3
100uL
Human
Flow Cytometry, IP, IHC-P, WB
$299
Cat # M03913-2
0.1 mg
Cat # M03913-2
0.1 mg
Human
ELISA, Flow Cytometry, IF, IHC, WB
$380
Cat # M00529-1
100ul
Cat # M00529-1
100ul
Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00602-5
20μL, 40μL, 100μL, 200μL
Cat # M00602-5
20μL, 40μL, 100μL, 200μL
Anti-Early activation antigen CD69 CD69 Antibody
1 Citations
Human, Mouse, Rat
WB
$405
Cat # A00529
100ul
Cat # A00529
100ul
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01080-4
20μL, 40μL, 100μL, 200μL
Cat # M01080-4
20μL, 40μL, 100μL, 200μL
Human
Flow Cytometry, IP, IHC-P, ICC
$301
Cat # M01080-2
0.1 mg
Cat # M01080-2
0.1 mg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00923-3
100 μg
Cat # M00923-3
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356-6
100 μg
Cat # M00356-6
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356-5
100 μg
Cat # M00356-5
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356
100 μg
Cat # M00356
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03913-3
100 μg
Cat # M03913-3
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00529-2
100 μg
Cat # M00529-2
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02428-3
100 μg/vial
Cat # A02428-3
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M31965
100 μg
Cat # M31965
100 μg
Human, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03674-2
100 μg
Cat # M03674-2
100 μg
Human, Primate
Flow Cytometry, IP, IHC-F, ICC, WB
$299
Cat # M01241-1
0.1 mg
Cat # M01241-1
0.1 mg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00923-4
100 μg
Cat # M00923-4
100 μg
Human
Flow Cytometry, IP, IHC-F, WB
$299
Cat # M00652-2
0.1 mg
Cat # M00652-2
0.1 mg
Mouse
Flow Cytometry, IP, IHC-P, IHC-F, ICC
$299
Cat # M00652-1
0.1 mg
Cat # M00652-1
0.1 mg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356-9
100 μg
Cat # M00356-9
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356-8
100 μg
Cat # M00356-8
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356-7
100 μg
Cat # M00356-7
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00356-10
100 μg
Cat # M00356-10
100 μg
Human, Mouse, Rat
ELISA, WB
$380
Cat # A00529-1
100ul
Cat # A00529-1
100ul
Human CEACAM-5/CD66e Recombinant Protein
1 Citations
SDS-PAGE
$250
Cat # PROTP06731
Starting from 10ug
Cat # PROTP06731
Starting from 10ug
SDS-PAGE, Bioactivity
$247
Cat # PROTP16581-3
Starting from 10ug
Cat # PROTP16581-3
Starting from 10ug
Cow, Human
Flow Cytometry, IP, ICC
$299
Cat # M00652
0.1 mg
Cat # M00652
0.1 mg
CD6 Overview
Facts about T-cell differentiation antigen CD6.
T-cell differentiation antigen CD6 (CD6)
Cell adhesion molecule that mediates cell-cell contacts and modulates T-cell responses through its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24945728, PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089).
Functions as costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938, PubMed:16352806, PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938, PubMed:16352806).
Gene Information
| Human | |
|---|---|
| Gene Name: | CD6 |
| Uniprot: | P30203 |
| Entrez: | 923 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD6 antigenFLJ44171; CD6 molecule; CD6; T12; Tp120; TP120T-cell differentiation antigen CD6
Molecular Weight
Mass (kDA):
71.801 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q12.2 |
| Sequence: | 11; NC_000011.10 (60971678..61020377) |
Tissue Specificity
Detected on thymocytes (PubMed:15294938). Detected on peripheral blood T-cells (PubMed:15048703, PubMed:16352806). Detected on natural killer (NK) cells (PubMed:16352806). Soluble CD6 is detected in blood serum (at protein level) (PubMed:17601777). Detected in spleen, thymus, appendix, lymph node and peripheral blood leukocytes (PubMed:9013954). Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with the TCR/CD3 complex at the immunological synapse (PubMed:15294938).; [Soluble CD6]: Secreted. The origins of the secreted form are not clear, but it might be created by proteolytic shedding of the ectodomain.
Diseases
- Tissue Adhesions
- Leukemia
- Graft-vs-host Disease
- Neoplasms
- Lymphoid Leukemia
- Malignant Neoplasms
- Lymphoma
- Sclerosis
- Chronic Lymphocytic Leukemia
- Acute Lymphocytic Leukemia
- Autoimmune Reaction
- Malignant Paraganglionic Neoplasm
- Inflammation
Interacting Proteins
- ALCAM
- LCP2
- LGALS1
- LGALS3
Pathways
- Cell Adhesion
- Cell Activation
- T Cell Activation
- Cell Proliferation
- Immune Response
- T Cell Proliferation
- Localization
- Leukocyte Differentiation
- Pathogenesis
- Lymphocyte Activation
- Cell Death
- Cell Differentiation
- Regulation Of T Cell Activation
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Carboxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD6
bosterbio.com/bosterbio-gene-info-cards/CD6
References
PMID: 9013954 by Bowen M.A., et al. Structure and chromosomal location of the human CD6 gene: detection of five human CD6 isoforms.
PMID: 1919444 by Aruffo A., et al. The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins.
119 Publications of Boster CD6 Antibodies & ELISA Kits
- PubMed ID: 10.5021/ad.2015.27.2.121, Retinoic Acid Promotes Interleukin-4 Plasmid-Dimethylsulfoxide Topical Transderm...
- PubMed ID: 10.3892/mmr.2016.5294, Effects of the eukaryotic initiation factor 6 gene on expression levels of infla...
- PubMed ID: 10.3892/ijmm.2018.3547, CFTR ameliorates high glucose-induced oxidative stress and inflammation by media...
- PubMed ID: 10.3390/ijms20082014, Targeting Brain Disease in MPSII: Preclinical Evaluation of IDS-Loaded PLGA Nano...
- PubMed ID: 10.1371/journal.pone.0140222, FGF-23/Vitamin D Axis in Type 1 Diabetes: The Potential Role of Mineral Metaboli...
- PubMed ID: 10.1186/s13046-020-01752-2, MiRNA-340-5p mediates the functional and infiltrative promotion of tumor-infiltr...
- PubMed ID: 10.1158/1535-7163.MCT-15-0995,
HPMA–Copolymer Nanocarrier Targets Tumor-Associated Macrophages in...
- PubMed ID: 10.1155/2020/8183713, ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endopl...
- PubMed ID: 10.1152/ajpendo.00208.2011, Globular adiponectin counteracts VCAM-1-mediated monocyte adhesion via AdipoR1/N...
- PubMed ID: 10.1136/jitc-2019-000172, Multifaceted effects of soluble human CD6 in experimental cancer models
- PubMed ID: 10.1111/eci.12487, Haptoglobin genotype is associated with increased endothelial dysfunction serum ...
- PubMed ID: 10.1080/07315724.2014.891269, Hesperidin Supplementation Modulates Inflammatory Responses Following Myocardial...
- PubMed ID: 10.1038/s41419-019-1599-9, MicroRNA-181a-5p and microRNA-181a-3p cooperatively restrict vascular inflammati...
- PubMed ID: 10.1038/jhh.2016.34, Improvement of hypertension, endothelial function and systemic inflammation foll...
- PubMed ID: 10.1016/j.snb.2014.09.084, An aptasensor for carcinoembryonic antigen based on upconversion fluorescence re...
- PubMed ID: 10.1016/j.colsurfb.2012.02.018, Fabrication of biomolecule-PEG micropattern on titanium surface and its effects ...
- PubMed ID: 10.1016/j.bbalip.2016.03.022, A novel anti-inflammatory mechanism of high density lipoprotein through up-regul...
- PubMed ID: 10.1007/s40618-015-0287-6, 1,25(OH) 2 D 3 downregulates the Toll-like receptor 4-mediated inflammatory path...
- PubMed ID: 10.1007/s10753-014-9918-x, Simvastatin Inhibits Inflammation in Ischemia-Reperfusion Injury
- PubMed ID: 10.1007/s10529-021-03148-4, Serum-derived exosomes accelerate scald wound healing in mice by optimizing cell...
- PubMed ID: , Fluorescence resonance energy transfer biosensor between upconverting nanopartic...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page