Anti-Hu CD116 Purified CSF2RA Monoclonal Antibody

GM-CSFR alpha antibody

Boster Bio Anti-Hu CD116 Purified CSF2RA Monoclonal Antibody (Catalog# M04432). Tested in Flow Cytometry, IP, WB, IHC-F, MC (CyTOF) application(s). This antibody reacts with Human.

Product Info Summary

SKU: M04432
Size: 0.1 mg
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IP, IHC-F, WB, CyTOF

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Product Name

Anti-Hu CD116 Purified CSF2RA Monoclonal Antibody

View all GM-CSFR alpha Antibodies

SKU/Catalog Number

M04432

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD116 Purified CSF2RA Monoclonal Antibody (Catalog# M04432). Tested in Flow Cytometry, IP, WB, IHC-F, MC (CyTOF) application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD116 Purified CSF2RA Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04432)

Host

Mouse

Contents

Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

4H1

Isotype

Mouse IgG1 kappa

Immunogen

CD116-transfected COS cells. The mouse monoclonal antibody 4H1 recognizes an extracellular epitope of human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M04432 is reactive to CSF2RA in Human

Applications

M04432 is guaranteed for Flow Cytometry, IP, IHC-F, WB, CyTOF Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

46.207kDa

Background of GM-CSFR alpha

CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5- receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

Gene/Protein Information For CSF2RA (Source: Uniprot.org, NCBI)

Gene Name

CSF2RA

Full Name

Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

Weight

46.207kDa

Superfamily

type I cytokine receptor family

Alternative Names

CD116 antigen; CD116; CDw116; colony stimulating factor 2 receptor alpha subunit; colony stimulating factor 2 receptor, alpha, low-affinity(granulocyte-macrophage); CSF2R; CSF2RA; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF R alpha; GM-CSF receptor alpha subunit; GMCSFR alpha; GMCSFR; GM-CSFRa; GM-CSF-R-alpha; GMCSFR-alpha; GMR; GMR-alpha; granulocyte-macrophage colony-stimulating factor receptor alpha chain; granulocyte-macrophage colony-stimulating factor receptor subunit alpha; MGC3848; MGC4838 CSF2RA CD116, CDw116, CSF2RX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMCSFR-alpha, GMR, GMR-alpha, SMDP4, alphaGMR, CSF2RA colony stimulating factor 2 receptor subunit alpha granulocyte-macrophage colony-stimulating factor receptor subunit alpha|CD116 antigen|GM-CSF receptor alpha subunit|alpha-GM-CSF receptor|colony stimulating factor 2 receptor alpha subunit|colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)|granulocyte-macrophage colony-stimulating factor receptor alpha chain

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CSF2RA, check out the CSF2RA Infographic

CSF2RA infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CSF2RA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M04432

0.1 mg

$291

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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