Anti-Hu CD200 Purified Monoclonal Antibody

CD200/OX2 antibody

Boster Bio Anti-Hu CD200 Purified Monoclonal Antibody (Catalog# M01512). Tested in Flow Cytometry, IHC-P, IHC-F application(s). This antibody reacts with Human.

Product Info Summary

SKU: M01512
Size: 0.1 mg
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IHC-P, IHC-F

Product Name

Anti-Hu CD200 Purified Monoclonal Antibody

View all CD200/OX2 Antibodies

SKU/Catalog Number

M01512

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD200 Purified Monoclonal Antibody (Catalog# M01512). Tested in Flow Cytometry, IHC-P, IHC-F application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD200 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01512)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

OX-104

Isotype

Mouse IgG1 kappa

Immunogen

Recombinant human CD200. The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01512 is reactive to CD200 in Human

Applications

M01512 is guaranteed for Flow Cytometry, IHC-P, IHC-F Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

31.264kDa

Background of CD200/OX2

CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

Gene/Protein Information For CD200 (Source: Uniprot.org, NCBI)

Gene Name

CD200

Full Name

OX-2 membrane glycoprotein

Weight

31.264kDa

Alternative Names

antigen identified by monoclonal MRC OX-2; CD200 antigenMOX1; CD200 molecule; CD200; MOX1; MOX2; MOX2MRC; MRC OX-2 antigen; MRC; OX-2 membrane glycoprotein; OX-2 CD200 MOX1, MOX2, MRC, OX-2 CD200 molecule OX-2 membrane glycoprotein|CD200 antigen|antigen identified by monoclonal antibody MRC OX-2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CD200, check out the CD200 Infographic

CD200 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CD200: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01512

0.1 mg

$291

Free Secondary Antibody

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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