Anti-Hu CD200 Purified Monoclonal Antibody

Product Name

Anti-Hu CD200 Purified Monoclonal Antibody

View all CD200 Antibodies

SKU/Catalog Number

M01512

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD200 Purified Monoclonal Antibody (Catalog# M01512). Tested in Flow Cytometry, IHC-P, IHC-F application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD200 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01512)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

OX-104

Isotype

Mouse IgG1 kappa

Immunogen

Recombinant human CD200. The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.

Reactive Species

M01512 is reactive to CD200 in Human

Observed Molecular Weight

42 kDa

Calculated molecular weight

31.3 kDa

Background of CD200

CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M01512 is guaranteed for Flow Cytometry, IHC-P, IHC-F Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

See full target information CD200

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