Anti-Kv4.1 (N588) KCND1 Antibody

Product Name

Anti-Kv4.1 (N588) KCND1 Antibody

View all Kv4.1 Antibodies

SKU/Catalog Number

A11599

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Kv4.1 (N588) KCND1 Antibody catalog # A11599. Tested in WB,IHC applications. This antibody reacts with Human,Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Kv4.1 (N588) KCND1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11599)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human GK2

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A11599 is reactive to KCND1 in Human, Mouse

Applications

A11599 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

71.33kDa

Background of Kv4.1

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform mayact as a negative regulator of normal cell cycle progression.

Bunnell B.A., Proc. Natl. Acad. Sci. U.S.A. 87:7467-7471(1990).
Eipers P.G., Genomics 13:613-621(1992).
Xiang J., J. Biol. Chem. 269:15786-15794(1994).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Immunohistochemistry validation of KCND1 using Anti-Kv4.1 (N588) KCND1 Antibody (A11599).

Immunohistochemistry (IHC) analyzes of Kv4.1 (N588) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.
For more protocol information of IHC

Gene/Protein Information For KCND1 (Source: Uniprot.org, NCBI)

Alternative Names

Kv4.1; potassium voltage-gated channel subfamily D member 1; potassium voltage-gated channel, Shal-related subfamily, member 1; shal-type potassium channel; voltage-gated potassium channel Kv4.1; Voltage-gated potassium channel subunit Kv4.1 KCND1 KV4.1 potassium voltage-gated channel subfamily D member 1 potassium voltage-gated channel subfamily D member 1|Shal-type potassium channel|potassium channel, voltage gated Shal related subfamily D, member 1|potassium voltage-gated channel, Shal-related subfamily, member 1|voltage-gated potassium channel subunit Kv4.1

For more info on KCND1, check out the KCND1 Infographic

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In this infographic, you will see the following information for KCND1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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