Anti-LKB1/STK11 Antibody Picoband™

Boster Bio Anti-LKB1/STK11 Antibody Picoband™ catalog # PB9270. Tested in WB applications. This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: PB9270
Size: 100μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

Product Name

Anti-LKB1/STK11 Antibody Picoband™

See all LKB1/STK11 products

SKU/Catalog Number

PB9270

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-LKB1/STK11 Antibody Picoband™ catalog # PB9270. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LKB1/STK11 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9270)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

E.coli-derived human LKB1 recombinant protein (Position: K62-C430). Human LKB1 shares 89% amino acid (aa) sequence identity with both mouse and rat LKB1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PB9270 is reactive to STK11 in Human

Applications

PB9270 is guaranteed for WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For STK11 (Source: Uniprot.Org, NCBI)

Uniprot ID

Q15831

Gene ID

6794

Gene Name

STK11

Full Name

Serine/threonine-protein kinase STK11

Weight

48.636kDa

Superfamily

protein kinase superfamily

Alternative Names

EC 2.7.11.1; LKB1 serine/threonine kinase 11 (Peutz-Jeghers syndrome); LKB1; PJS polarization-related protein LKB1; PJS; Renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; Serine/threonine-protein kinase LKB1; STK11 STK11 LKB1, PJS, hLKB1 serine/threonine kinase 11 serine/threonine-protein kinase STK11|liver kinase B1|polarization-related protein LKB1|renal carcinoma antigen NY-REN-19|serine/threonine-protein kinase 11|serine/threonine-protein kinase LKB1

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on STK11, check out the STK11 Infographic

STK11 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for STK11: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PB9270 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Tang Y, Li M, Wang Yl, Threadgill Md, Xiao M, Mou Cf, Song Gl, Kuang J, Yang X, Yang L, Gao Xj, Wang Yp, Meng Yp. Am J Cancer Res. 2015 Jan 15;5(2):498-513. Ecollection 2015. Art1 Promotes Starvation-Induced Autophagy: A Possible Protective Role I...

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4 Customer Q&As for Anti-LKB1/STK11 Antibody Picoband™

Question

We are currently using anti-LKB1/STK11 antibody PB9270 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2020-04-03

Answer

The anti-LKB1/STK11 antibody (PB9270) has not been validated for cross reactivity specifically with goat tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-04-03

Question

I was wanting to use using your anti-LKB1/STK11 antibody for negative regulation of cell growth studies. Has this antibody been tested with western blotting on 293t whole cell lysate? We would like to see some validation images before ordering.

Verified Customer

Verified customer

Asked: 2018-04-16

Answer

We appreciate your inquiry. This PB9270 anti-LKB1/STK11 antibody is validated on human placenta tissue, 293t whole cell lysate, ht1080 whole cell lysate, shg whole cell lysate, jurkat whole cell lysate, tissue lysate. It is guaranteed to work for WB in human. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2018-04-16

Question

We have been able to see staining in human brain. What should we do? Is anti-LKB1/STK11 antibody supposed to stain brain positively?

D. Evans

Verified customer

Asked: 2018-02-05

Answer

According to literature brain does express STK11. According to Uniprot.org, STK11 is expressed in testis, liver, brain, lung uterus, renal cell carcinoma, erythroleukemia, among other tissues. Regarding which tissues have STK11 expression, here are a few articles citing expression in various tissues:
Brain, Pubmed ID: 14702039
Erythroleukemia, Pubmed ID: 23186163
Liver, Pubmed ID: 9425897, 24275569
Lung, and Uterus, Pubmed ID: 15489334
Renal cell carcinoma, Pubmed ID: 10508479, 11212897

Boster Scientific Support

Answered: 2018-02-05

Question

My colleagues were satisfied with the WB result of your anti-LKB1/STK11 antibody. However we have observed positive staining in renal cell carcinoma isoform 2: nucleus using this antibody. Is that expected? Could you tell me where is STK11 supposed to be expressed?

A. Zhang

Verified customer

Asked: 2014-06-20

Answer

From what I have seen in literature, renal cell carcinoma does express STK11. Generally STK11 expresses in nucleus. cytoplasm. membrane., isoform 2: nucleus. Regarding which tissues have STK11 expression, here are a few articles citing expression in various tissues:
Brain, Pubmed ID: 14702039
Erythroleukemia, Pubmed ID: 23186163
Liver, Pubmed ID: 9425897, 24275569
Lung, and Uterus, Pubmed ID: 15489334
Renal cell carcinoma, Pubmed ID: 10508479, 11212897

Boster Scientific Support

Answered: 2014-06-20

Size

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PB9270
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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