Anti-HIF1 beta/ARNT Antibody Picoband™

ARNT/HIF-1 beta antibody

Boster Bio Anti-HIF1 beta/ARNT Antibody Picoband™ catalog # PB9129. Tested in WB applications. This antibody reacts with Human. Cited in 10 publication(s).

Product Info Summary

SKU: PB9129
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-HIF1 beta/ARNT Antibody Picoband™

View all ARNT/HIF-1 beta Antibodies

SKU/Catalog Number

PB9129

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-HIF1 beta/ARNT Antibody Picoband™ catalog # PB9129. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HIF1 beta/ARNT Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9129)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human HIF1 beta recombinant protein (Position: V416-E789). Human HIF1 beta shares 86% and 83% amino acid (aa) sequences identity with mouse and rat HIF1 beta, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9129 is reactive to ARNT in Human

Applications

PB9129 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

87 kDa

Calculated molecular weight

86.636kDa

Background of ARNT/HIF-1 beta

ARNT is also known as HIF1-beta or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. ARNT is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For ARNT (Source: Uniprot.org, NCBI)

Gene Name

ARNT

Full Name

Aryl hydrocarbon receptor nuclear translocator

Weight

86.636kDa

Alternative Names

ARNT protein; ARNT; aryl hydrocarbon receptor nuclear translocator; BHLHE2; HIF1 beta; HIF-1 beta; HIF1B; HIF1BETA; HIF-1-beta; HIF1-beta; hypoxia-inducible factor 1, beta subunit; Hypoxia-inducible factor 1-beta; nuclear translocator; TANGO ARNT HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator aryl hydrocarbon receptor nuclear translocator|class E basic helix-loop-helix protein 2|dioxin receptor, nuclear translocator|hypoxia-inducible factor 1, beta subunit

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ARNT, check out the ARNT Infographic

ARNT infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ARNT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9129 has been cited in 10 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

TLR4 promotes the expression of HIF-1? by triggering reactive oxygen species in cervical cancer cells in vitro-implications for therapeutic intervention

Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth

Suppression of the expression of hypoxia-inducible factor-1? by RNA interference alleviates hypoxia-induced pulmonary hypertension in adult rats

Effect of rapamycin on endometriosis in mice

Hypoxic preconditioning increases the protective effect of bone marrow mesenchymal stem cells on spinal cord ischemia/reperfusion injury

Local recurrence of small cell lung cancer following radiofrequency ablation is induced by HIF-1? expression in the transition zone

Effect of Hyperbaric Oxygen on the Growth of Intracranial Glioma in Rats

Increased hypoxia-inducible factor 1alpha expression in rat brain tissues in response to aging

Semaphorin 4D and hypoxia-inducible factor-1? overexpression is related to prognosis in colorectal carcinoma

Evidence for a therapeutic effect of Braintone on ischemic brain damage

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1 Customer Q&As for Anti-HIF1 beta/ARNT Antibody Picoband™

Question

We are currently using anti-HIF1 beta/ARNT antibody PB9129 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on goat tissues as well?

R. Evans

Verified customer

Asked: 2019-12-18

Answer

The anti-HIF1 beta/ARNT antibody (PB9129) has not been tested for cross reactivity specifically with goat tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-12-18

Order DetailsPrice
PB9129

100μg

$370
PB9129-10ug

10μg sample (liquid)

$99
PB9129-Biotin

100 μg Biotin conjugated

$570
PB9129-Cy3

100 μg Cy3 conjugated

$570
PB9129-Dylight488

100 μg Dylight488 conjugated

$570
PB9129-Dylight550

100 μg Dylight550 conjugated

$570
PB9129-Dylight594

100 μg Dylight594 conjugated

$570
PB9129-FITC

100 μg FITC conjugated

$570
PB9129-HRP

100 μg HRP conjugated

$570
PB9129-APC

100 μg APC conjugated

$670
PB9129-PE

100 μg PE conjugated

$670
PB9129-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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