Anti-Matrix metalloproteinase-16 MMP16 Antibody

MMP-16/MT3-MMP antibody

Boster Bio Anti-Matrix metalloproteinase-16 MMP16 Antibody catalog # PA1123. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 3 publication(s).

Product Info Summary

SKU: PA1123
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: IHC, IHC-F, WB

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Product Name

Anti-Matrix metalloproteinase-16 MMP16 Antibody

View all MMP-16/MT3-MMP Antibodies

SKU/Catalog Number



100 μg/vial




Boster Bio Anti-Matrix metalloproteinase-16 MMP16 Antibody catalog # PA1123. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Matrix metalloproteinase-16 MMP16 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1123)




Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.




Rabbit IgG


A synthetic peptide corresponding to a sequence at the C-terminus of human MMP16 (582-598aa, YTVFQFKRKGTPRHILY), identical to the related rat and mouse sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.


No cross-reactivity with other proteins

Reactive Species

PA1123 is reactive to MMP16 in Human, Rat


PA1123 is guaranteed for IHC, IHC-F, WB Boster Guarantee

Background of MMP-16/MT3-MMP

The matrix metalloproteinase 16 (MMP16) protein consists of 604 amino acids and has a characteristic MMP domain structure, which gene is mapped on human chromosome 8q21. Additionally, MMP16 has a C-terminal extension containing a potential transmembrane domain, similar to MMP14 , MMP15 , and MMP17. Furthermore, it is membrane-bound and is a member of the membrane-type MMPs that are a subclass in the MMP family since the other members lack a C-terminal transmembrane domain and are secreted as soluble forms. MMP16 is expressed as a 12-kb transcript in brain, placenta, heart, and some carcinoma cell lines, but is not detectably expressed in lung, kidney, liver, spleen, and muscle.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For MMP16 (Source:, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name

Matrix metalloproteinase-16




peptidase M10A family

Alternative Names

chromosome 8 open reading frame 57; DKFZp761D112; EC 3.4.24; EC 3.4.24.-; EC; matrix metallopeptidase 16 (membrane-inserted); matrix metalloproteinase 16 (membrane-inserted); matrix metalloproteinase-16; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase; MMP16; MMP-16; MMPX2; MMP-X2; MT3MMP; MT3-MMP; MT3-MMPC8orf57; MT-MMP 3; MT-MMP2; MTMMP3; MT-MMP3; Putative transmembrane protein C8orf57 MMP16 C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP matrix metallopeptidase 16 matrix metalloproteinase-16|MMP-16|MT-MMP 3|MT3MMP|MTMMP3|Putative transmembrane protein C8orf57|matrix metallopeptidase 16 (membrane-inserted)|membrane-type matrix metalloproteinase 3|membrane-type-3 matrix metalloproteinase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MMP16, check out the MMP16 Infographic

MMP16 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MMP16: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

PA1123 has been cited in 3 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma

miR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro

Lin F, Wang X, Jie Z, Hong X, Li X, Wang M, Yu Y. J Huazhong Univ Sci Technolog Med Sci. 2011 Aug;31(4):509-14. Doi: 10.1007/S11596-011-0481-5. Epub 2011 Aug 7. Inhibitory Effects Of Mir-146B-5P On Cell Migration And Invasion Of Pancreatic Cancer ...

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3 Customer Q&As for Anti-Matrix metalloproteinase-16 MMP16 Antibody


We are currently using anti-MMP16 antibody PA1123 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on dog tissues as well?

Verified Customer

Verified customer

Asked: 2020-03-30


The anti-MMP16 antibody (PA1123) has not been tested for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-03-30


Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for brain using anti-MMP16 antibody PA1123. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2019-07-10


We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-07-10


See below the WB image, lot number and protocol we used for brain using anti-MMP16 antibody PA1123. Please let me know if you require anything else.

A. Yang

Verified customer

Asked: 2019-01-31


Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-01-31



Total: $315


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