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- Table of Contents
MMP16 Antibodies
AND MMP16 ELISA kits, MMP16 Proteins
Many biological assays use antibodies to detect MMP16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MMP16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MMP16 antibodies...
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MMP16 Infographic by Boster Bio
All MMP16 Products
Product
Figures
Specificity
Applications
Price
Anti-Matrix metalloproteinase-16 MMP16 Antibody Picoband®
6 Citations 3 Q&As
Human, Rat
IHC, IHC-F, WB
$370
Cat # PA1123
100 μg/vial
Cat # PA1123
100 μg/vial
Anti-MMP16 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05065
100 μg/vial
Cat # A05065
100 μg/vial
MMP16 Overview
Facts about Matrix metalloproteinase-16.
Matrix metalloproteinase-16 (MMP16)
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A.
Involved in the matrix remodeling of blood vessels. Isoform brief cleaves fibronectin and additionally collagen type III, but at lower speed.
Gene Information
| Human | |
|---|---|
| Gene Name: | MMP16 |
| Uniprot: | P51512 |
| Entrez: | 4325 |
Family
| Belongs to: |
|---|
| peptidase M10A family |
Alternative Names
chromosome 8 open reading frame 57; DKFZp761D112; EC 3.4.24; EC 3.4.24.-; EC 3.4.24.80; matrix metallopeptidase 16 (membrane-inserted); matrix metalloproteinase 16 (membrane-inserted); matrix metalloproteinase-16; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase; MMP16; MMP-16; MMPX2; MMP-X2; MT3MMP; MT3-MMP; MT3-MMPC8orf57; MT-MMP 3; MT-MMP2; MTMMP3; MT-MMP3; Putative transmembrane protein C8orf57
Molecular Weight
Mass (kDA):
69.521 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q21.3 |
| Sequence: | 8; NC_000008.11 (88032009..88327483, complement) |
Tissue Specificity
Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Subcellular Localizations
[Isoform Long]: Cell membrane; Single-pass type I membrane protein; Extracellular side. Localized at the cell surface of melanoma cells.; [Isoform Short]: Secreted, extracellular space, extracellular matrix. Cell surface. Localized at the cell surface of melanoma cells.
Diseases
- Neoplasms
- Cell Invasion
- Malignant Neoplasms
- Neoplasm Invasiveness
- Carcinoma
- Neoplasm Metastasis
- Glioma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Dysplasia
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
Pathways
- Proteolysis
- Cell Migration
- Localization
- Tube Formation
- Tissue Remodeling
- Angiogenesis
- Cell Adhesion
- Endochondral Ossification
- Gland Development
- Lung Development
- Metaphase
- Ossification
- Mammary Gland Development
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMP16
bosterbio.com/bosterbio-gene-info-cards/MMP16
References
PMID: 7559440 by Takino T., et al. Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.
PMID: 9396633 by Matsumoto S., et al. Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA.
4 Publications of Boster MMP16 Antibodies & ELISA Kits
- PubMed ID: 10.3233/THC-218020, H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative str...
- PubMed ID: 27292876, MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis ...
- PubMed ID: 26604788, miR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro
- PubMed ID: 21823013, Lin F, Wang X, Jie Z, Hong X, Li X, Wang M, Yu Y. J Huazhong Univ Sci Technolog ...
*More publications can be found for each product on its corresponding product page