Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody

Boster Bio Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody catalog # M00211. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: M00211
Size: 100 μl
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody

See all MBP products

SKU/Catalog Number

M00211

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody catalog # M00211. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00211)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

IIE-13

Immunogen

A synthesized peptide derived from human Myelin Basic Protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00211 is reactive to MBP in Human

Applications

M00211 is guaranteed for IHC, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For MBP (Source: Uniprot.Org, NCBI)

Uniprot ID

P02686

Gene ID

4155

Gene Name

MBP

Full Name

Myelin basic protein

Weight

33.117kDa

Superfamily

myelin basic protein family

Alternative Names

Hmbpr; MBP; MGC99675; mld; Myelin A1 protein; myelin basic protein; Myelin membrane encephalitogenic protein; shi MBP myelin basic protein myelin basic protein|Golli-MBP|proline-rich proteoglycan 2|myelin A1 protein|myelin membrane encephalitogenic protein

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on MBP, check out the MBP Infographic

MBP infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for MBP: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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3 Customer Q&As for Anti-Myelin Basic Protein MBP Rabbit Monoclonal Antibody

Question

My team were satisfied with the WB result of your anti-Myelin Basic Protein Rabbit Monoclonal antibody. However we have been able to see positive staining in brain myelin membrane using this antibody. Is that expected? Could you tell me where is MBP supposed to be expressed?

Verified Customer

Verified customer

Asked: 2019-08-20

Answer

Based on literature, brain does express MBP. Generally MBP expresses in myelin membrane. Regarding which tissues have MBP expression, here are a few articles citing expression in various tissues:
Amygdala, Pubmed ID: 17974005
Brain, Pubmed ID: 7504278, 7574672, 7685161
Cervix carcinoma, Pubmed ID: 23186163
Embryonic spinal cord, Pubmed ID: 2427738, 2442403
Hippocampus, and Subthalamic nucleus, Pubmed ID: 14702039
Leukemic T-cell, Pubmed ID: 19690332

Boster Scientific Support

Answered: 2019-08-20

Question

We are currently using anti-Myelin Basic Protein Rabbit Monoclonal antibody M00211 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on zebrafish tissues as well?

Verified Customer

Verified customer

Asked: 2017-07-12

Answer

The anti-Myelin Basic Protein Rabbit Monoclonal antibody (M00211) has not been validated for cross reactivity specifically with zebrafish tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-07-12

Question

We have seen staining in human leukemic t-cell. What should we do? Is anti-Myelin Basic Protein Rabbit Monoclonal antibody supposed to stain leukemic t-cell positively?

Verified Customer

Verified customer

Asked: 2017-05-12

Answer

From what I have seen in literature leukemic t-cell does express MBP. From what I have seen in Uniprot.org, MBP is expressed in c1 segment of cervical spinal cord, embryonic spinal cord, brain, amygdala, hippocampus subthalamic nucleus, brain, lung skin, leukemic t-cell, cervix carcinoma, among other tissues. Regarding which tissues have MBP expression, here are a few articles citing expression in various tissues:
Amygdala, Pubmed ID: 17974005
Brain, Pubmed ID: 7504278, 7574672, 7685161
Cervix carcinoma, Pubmed ID: 23186163
Embryonic spinal cord, Pubmed ID: 2427738, 2442403
Hippocampus, and Subthalamic nucleus, Pubmed ID: 14702039
Leukemic T-cell, Pubmed ID: 19690332

Boster Scientific Support

Answered: 2017-05-12

Size

Total: $315

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Ships directly to USA and Canada. For other regions, visit our distributors page

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M00211
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

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