Anti-ABCB4 Antibody

MDR3/ABCB4 antibody

Boster Bio Anti-ABCB4 Antibody catalog # PA2090. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: PA2090
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-ABCB4 Antibody

View all MDR3/ABCB4 Antibodies

SKU/Catalog Number

PA2090

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-ABCB4 Antibody catalog # PA2090. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ABCB4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2090)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ABCB4.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2090 is reactive to ABCB4 in Human

Applications

PA2090 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

142 kDa

Calculated molecular weight

141.523kDa

Background of MDR3/ABCB4

Adenosine triphosphate-binding cassette subfamily B, member 4 (ABCB4), also called MDR3, is a protein that in humans is encoded by the ABCB4 gene. MDR1 and MDR3 constitute the human P-glycoprotein gene family. The MDR3 gene contains 28 exons and 27 of these contain coding sequences for the two homologous halves of the protein that correlate with functional domains. MDR3 gene mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For ABCB4 (Source: Uniprot.org, NCBI)

Gene Name

ABCB4

Full Name

Phosphatidylcholine translocator ABCB4

Weight

141.523kDa

Superfamily

ABC transporter superfamily

Alternative Names

ABC21; ABCB4; ATP-binding cassette sub-family B member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4; EC 3.6.3; EC 3.6.3.44; GBD1; MDR2; MDR3; MDR3MDR2/3; multidrug resistance protein 3; multiple drug resistance 3; P glycoprotein 3/multiple drug resistance 3; PFIC-3; P-glycoprotein 3; P-glycoprotein-3/multiple drug resistance-3; PGY3; PGY3GBD1 ABCB4 ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3 ATP binding cassette subfamily B member 4 phosphatidylcholine translocator ABCB4|ATP-binding cassette sub-family B member 4|ATP-binding cassette, sub-family B (MDR/TAP), member 4|P-glycoprotein 3|P-glycoprotein-3/multiple drug resistance-3|multidrug resistance protein 3|multiple drug resistance 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ABCB4, check out the ABCB4 Infographic

ABCB4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ABCB4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Conjugation

Total: $370

SKU:PA2090

In stock, 3+ left.

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PA2090
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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