Anti-PAPP-A Antibody (Monoclonal, ABM4C62)

Product Name

Anti-PAPP-A Antibody (Monoclonal, ABM4C62)

View all PAPPA Antibodies

SKU/Catalog Number

M06838

Size

100 µg

Form

Liquid

Description

Boster Bio Anti-PAPP-A Antibody (Monoclonal, ABM4C62) (Catalog# M06838). Tested in IHC application(s). This antibody reacts with Human.

Storage & Handling

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Cite This Product

Anti-PAPP-A Antibody (Monoclonal, ABM4C62) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M06838)

Host

Mouse

Contents

100 µg in 200 µl PBS containing 0.05% stabilizing protein and 0.05% sodium azide
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Monoclonal

Clone Number

ABM4C62

Isotype

IgG2b Kappa

Immunogen

A partial length recombinant PAPP-A protein (amino acids 332-561)

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M06838 is reactive to PAPPA in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

181.0 kDa

Background of PAPPA

Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M06838 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 5-10 µg/ml

Validation Images & Assay Conditions

See full target information PAPPA

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