Product Info Summary
SKU: | A00491-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-PDX1 Antibody
View all PDX-1/IPF1 Antibodies
SKU/Catalog Number
A00491-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PDX1 Antibody catalog # A00491-1. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PDX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00491-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant full length Human PDX1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00491-1 is reactive to PDX1 in Human
Applications
A00491-1 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
30.771kDa
Background of PDX-1/IPF1
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
WB: 1:500
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunofluorescent staining data of PDX1 using Anti-PDX1 Antibody (A00491-1).
IF analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody (green). The nuclear counter stain is DAPI (blue).Click image to see more details
Figure 1. Immunohistochemistry validation of PDX1 using Anti-PDX1 Antibody (A00491-1).
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody. Counter stained with hematoxylin.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For PDX1 (Source: Uniprot.org, NCBI)
Gene Name
PDX1
Full Name
Pancreas/duodenum homeobox protein 1
Weight
30.771kDa
Superfamily
Antp homeobox family
Alternative Names
Glucose-sensitive factor; IDX1; IDX-1GSF; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; Insulin upstream factor 1; IPF1; IPF1pancreas/duodenum homeobox protein 1; Islet/duodenum homeobox-1; MODY4IUF1; pancreatic and duodenal homeobox 1; pancreatic-duodenal homeobox factor 1; PDX-1; PDX-1IPF-1; somatostatin transcription factor 1; Somatostatin-transactivating factor 1; STF-1IUF-1 PDX1 GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1 pancreatic and duodenal homeobox 1 pancreas/duodenum homeobox protein 1|IPF-1|IUF-1|glucose-sensitive factor|insulin promoter factor 1, homeodomain transcription factor|insulin upstream factor 1|islet/duodenum homeobox-1|pancreatic-duodenal homeobox factor 1|somatostatin transcription factor 1|somatostatin-transactivating factor 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PDX1, check out the PDX1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PDX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PDX1 Antibody (A00491-1)
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No publications found for A00491-1
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