PRKG2 Antibodies

AND PRKG2 ELISA kits, PRKG2 Proteins

Many biological assays use antibodies to detect PRKG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKG2 antibodies...

We validate the specificity of these antibodies to PRKG2 by testing them on tissues known to express PRKG2 positively and negatively. Browse below to find the PRKG2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PRKG2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PRKG2 IHC Guide

PRKG2 Infographic by Boster Bio

All PRKG2 Products

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Product

Figures

Specificity

Applications

Price

Anti-cGKII PRKG2 Antibody

Western Blot analysis of various cells using cGKII Polyclonal Antibody

Western Blot analysis of HuvEc cells using cGKII Polyclonal Antibody

Western blot analysis of lysates from HUVEC cells, using CGK 2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A05103
100μl

Anti-CGK 2 Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A30481
100ul

CGK 2 Colorimetric Cell-Based ELISA

Western blot analysis of extracts from HuvEc cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1792
1 kit, containing one 96-well plate and all necessary reagents

CGK2 (PRKG2) (NM_006259) Human Over-expression Lysate

Human

$960
Cat # LS005593
20 µg, 100 µg

Anti-PRKG2 Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A05103-1
100 μl/vial

PRKG2 Overview

Facts about cGMP-dependent protein kinase 2.

PRKG2 3D structure. Source: alphafold

cGMP-dependent protein kinase 2 (PRKG2)

Crucial regulator of intestinal secretion and bone growth (By similarity). Phosphorylates and activates CFTR on the plasma membrane.

Plays a vital role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum (By similarity). Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity.

Gene Information

Human
Gene Name:	PRKG2
Uniprot:	Q13237
Entrez:	5593

Family

Belongs to:

protein kinase superfamily

Alternative Names

cGMP-dependent protein kinase 2

Molecular Weight

Mass (kDA):
87.432 kDA

Genomic Context


Human

Location:	4q21.21
Sequence:	4; NC_000004.12 (81087370..81217837, complement)

Tissue Specificity

Highly concentrated in brain, lung and intestinal mucosa.

Subcellular Localizations

Apical cell membrane; Lipid-anchor.

PTMs

Lipoprotein

Myristate

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKG2

References

PMID: 8607838 by Orstavik S., et al. Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase.

PMID: 7498513 by Fujii M., et al. Expression of the human cGMP-dependent protein kinase II gene is lost upon introduction of SV40 T antigen or immortalization in human cells.