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- Table of Contents
TAL1 Antibodies
AND TAL1 ELISA kits, TAL1 Proteins
Many biological assays use antibodies to detect TAL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TAL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TAL1 antibodies...
Designing a Western blot for TAL1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TAL1 Western Blot GuideTAL1 Infographic by Boster Bio
All TAL1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1558
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1558
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, WB
$399
Cat # A00944-1
100μl
Cat # A00944-1
100μl
TAL1 Overview
Facts about T-cell acute lymphocytic leukemia protein 1.
T-cell acute lymphocytic leukemia protein 1 (TAL1)
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation.
Serves as a positive regulator of erythroid differentiation (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | TAL1 |
| Uniprot: | P17542 |
| Entrez: | 6886 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BHLHA17; bHLHa17tal-1; Class A basic helix-loop-helix protein 17; SCL; SCLT-cell acute lymphocytic leukemia protein 1; Stem Cell Protein; Tal1; TAL-1; T-cell acute lymphocytic leukemia 1; T-cell leukemia/lymphoma protein 5; TCL5; TCL5tal-1 product
Molecular Weight
Mass (kDA):
34.271 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p33 |
| Sequence: | 1; NC_000001.11 (47216290..47232389, complement) |
Tissue Specificity
Leukemic stem cell.
Subcellular Localizations
Nucleus.
Diseases
- Leukemia
- Acute Lymphocytic Leukemia
- Precursor T-cell Lymphoblastic Leukemia-lymphoma
- Adult T-cell Lymphoma/leukemia
- Acute Undifferentiated Leukemia
- Chromosomal Translocation
- Malignant Neoplasms
- Neoplasms
- Leukemogenesis
- Acute Erythroblastic Leukemia
- Leukemia, T-cell
- Cell Transformation, Neoplastic
- Lymphoma
Interacting Proteins
- ETS1
- Lmo2
- MYB
- RUNX1
- TCF12
- TCF3
Pathways
- Cell Differentiation
- Cell Development
- Angiogenesis
- Vasculogenesis
- Cell Cycle
- Pathogenesis
- Cell Proliferation
- Localization
- Methylation
- Fermentation
- Cell Growth
- Rna Interference
- Oncogenesis
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TAL1
bosterbio.com/bosterbio-gene-info-cards/TAL1
References
PMID: 2247063 by Aplan P.D., et al. The SCL gene is formed from a transcriptionally complex locus.
PMID: 2230650 by Chen Q., et al. Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia.