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Product Info Summary
| SKU: | A11935-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Slc35D1 Antibody
SKU/Catalog Number
A11935-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Slc35D1 Antibody (Catalog # A11935-1). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Slc35D1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Slc35D1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11935-1)
Host
Rabbit
Contents
Slc35D1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Slc35D1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human Slc35D1. The immunogen is located within the first 50 amino acids of Slc35D1.
Cross-reactivity
This antibody is predicted to not cross-react with the highly homologous Slc35D2.
Reactive Species
A11935-1 is reactive to SLC35D1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
39.2 kDa
Background of SLC35D1
The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11935-1 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Slc35D1 antibody can be used for detection of Slc35D1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Slc35D1 inA-20 lysate with Slc35D1 antibody at (A) 1 and (B) 2 μg/mL.
Specific Publications For Anti-Slc35D1 Antibody (A11935-1)
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