Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1)

Product Name

Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1)

View all Spectrin beta 1 Antibodies

SKU/Catalog Number

MA1090

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Spectrin (Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1) catalog # MA1090. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1090)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

SB-SP1

Isotype

Mouse IgG1

Immunogen

Human erythrocyte spectrin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

MA1090 is reactive to SPTB in Human

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Observed Molecular Weight

60 kDa

Calculated molecular weight

246329 MW

Background of Spectrin beta 1

Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

MA1090 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 2-4μg/ml, Human

Positive Control

Validation Images & Assay Conditions

Click image to see more details

Boster Kit Box

Gene/Protein Information For SPTB (Source: Uniprot.org, NCBI)

Alternative Names

beta-I spectrin; EL3; erythrocyte; HS2; HSPTB1; membrane cytoskeletal protein; spectrin, beta, erythrocytic; SPTB1 SPTB EL3, HS2, HSPTB1, SPH2 spectrin beta, erythrocytic spectrin beta chain, erythrocytic|Sp beta|beta-I spectrin|membrane cytoskeletal protein|spectrin beta Tandil|spectrin beta chain, erythrocyte

For more info on SPTB, check out the SPTB Infographic

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In this infographic, you will see the following information for SPTB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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