Anti-Spectrin(Alpha And Beta) Antibody (Monoclonal, SB-SP1)
|Ig Isotype||Mouse IgG1|
|Product Name||Anti-Spectrin(Alpha And Beta) Antibody (Monoclonal, SB-SP1)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for Spectrin(alpha and beta), spectrin, alpha, erythrocytic 1 (elliptocytosis 2); spectrin, beta, erythrocytic (SPTA1; SPTB ) detection. Tested with WB in Human. No cross reactivity with other proteins.|
|Cite This Product||Anti-Spectrin(Alpha And Beta) Antibody (Monoclonal, SB-SP1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1090)|
|Contents/Buffer||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Immunogen||Human erythrocyte spectrin.|
Assay Dilutions Overview
Western blot, 2-4μg/ml, Human
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot.
Images And Assay Conditions
Boster Kit Box
Protein Target Info (Source: Uniprot.org)
|Protein Name||spectrin, alpha, erythrocytic 1(elliptocytosis 2); spectrin, beta, erythrocytic|
|Alternative Names||Erythroid spectrin beta ;Sptb ;LOC314251 ;|
|Subcellular Localization||SPTA1: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.|Spta1: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.|SPTB: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.|Sptb: Cytoplasm, cytoskeleton. Cytoplasm, cellcortex.|
|Molecular Weight||246329 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||SPTA1: Spectrin is the major constituent of the cytoskeletalnetwork underlying the erythrocyte plasma membrane. It associateswith band 4.1 and actin to form the cytoskeletal superstructure ofthe erythrocyte plasma membrane.|SPTB: Spectrin is the major constituent of the cytoskeletalnetwork underlying the erythrocyte plasma membrane. It associateswith band 4.1 and actin to form the cytoskeletal superstructure ofthe erythrocyte plasma membrane.|
*You can search these to find other products in these research areas.
|Background||Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.|
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Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WBA: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugationA: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact email@example.com
Q: Can you provide monoclonal antibodies carrier free?A: For most of our monoclonal antibodies, we are unable to provide them carrier free. If you would like to check if a specific antibody can be provided carrier free, please send an email to firstname.lastname@example.org.
Q: What are some alternative names that could be used to describe this product?A: One other very common name is erythrocyte antibody