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Product Info Summary
| SKU: | A14266 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Synaptopodin 2-like protein SYNPO2L Antibody
SKU/Catalog Number
A14266
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Synaptopodin 2-like protein SYNPO2L Antibody (Catalog # A14266). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
SYNPO2L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Synaptopodin 2-like protein SYNPO2L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14266)
Host
Rabbit
Contents
SYNPO2L Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SYNPO2L antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SYNPO2L. The immunogen is located within amino acids 140 - 190 of SYNPO2L.
Reactive Species
A14266 is reactive to SYNPO2L in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
102.5 kDa
Background of SYNPO2L
SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A14266 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SYNPO2L antibody can be used for detection of SYNPO2L by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 20 μg/mL.
Specific Publications For Anti-Synaptopodin 2-like protein SYNPO2L Antibody (A14266)
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