Anti-TP53BP2 Antibody

53BP2 antibody

Boster Bio Anti-TP53BP2 Antibody catalog # A02609-1. Tested in WB applications. This antibody reacts with Human,Mouse.

Product Info Summary

SKU: A02609-1
Size: 100ul
Reactive Species: Human, Mouse
Host: Rabbit
Application: WB

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Product Name

Anti-TP53BP2 Antibody

View all 53BP2 Antibodies

SKU/Catalog Number

A02609-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TP53BP2 Antibody catalog # A02609-1. Tested in WB applications. This antibody reacts with Human,Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TP53BP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02609-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Y185.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02609-1 is reactive to TP53BP2 in Human, Mouse

Applications

A02609-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

125.616kDa

Background of 53BP2

p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For TP53BP2 (Source: Uniprot.org, NCBI)

Gene Name

TP53BP2

Full Name

Apoptosis-stimulating of p53 protein 2

Weight

125.616kDa

Superfamily

ASPP family

Alternative Names

apoptosis-stimulating protein of p53, 2; ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2; Bbp; Bcl2-binding protein; p53-binding protein 2; p53BP2; PPP1R13A; Renal carcinoma antigen NY-REN-51; tumor protein p53 binding protein, 2; tumor protein p53-binding protein, 2; Tumor suppressor p53-binding protein 2 TP53BP2 53BP2, ASPP2, BBP, P53BP2, PPP1R13A tumor protein p53 binding protein 2 apoptosis-stimulating of p53 protein 2|BCL2-binding protein|apoptosis-stimulating protein of p53, 2|renal carcinoma antigen NY-REN-51|tumor suppressor p53-binding protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TP53BP2, check out the TP53BP2 Infographic

TP53BP2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TP53BP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02609-1-100ul

100ul

$405

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