Product Info Summary
SKU: | A02609-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-TP53BP2 Antibody
SKU/Catalog Number
A02609-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TP53BP2 Antibody catalog # A02609-1. Tested in WB applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TP53BP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02609-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Y185.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02609-1 is reactive to TP53BP2 in Human, Mouse
Applications
A02609-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
125.616kDa
Background of 53BP2
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-TP53BP2 Antibody A02609-1
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For TP53BP2 (Source: Uniprot.org, NCBI)
Gene Name
TP53BP2
Full Name
Apoptosis-stimulating of p53 protein 2
Weight
125.616kDa
Superfamily
ASPP family
Alternative Names
apoptosis-stimulating protein of p53, 2; ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2; Bbp; Bcl2-binding protein; p53-binding protein 2; p53BP2; PPP1R13A; Renal carcinoma antigen NY-REN-51; tumor protein p53 binding protein, 2; tumor protein p53-binding protein, 2; Tumor suppressor p53-binding protein 2 TP53BP2 53BP2, ASPP2, BBP, P53BP2, PPP1R13A tumor protein p53 binding protein 2 apoptosis-stimulating of p53 protein 2|BCL2-binding protein|apoptosis-stimulating protein of p53, 2|renal carcinoma antigen NY-REN-51|tumor suppressor p53-binding protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TP53BP2, check out the TP53BP2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TP53BP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TP53BP2 Antibody (A02609-1)
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No publications found for A02609-1
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