Product Info Summary
SKU: | A00901Y1175 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-VEGFR2/Flk-1 (phospho-Y1175) KDR Antibody
View all VEGFR2/KDR/Flk-1 Antibodies
SKU/Catalog Number
A00901Y1175
Size
100ul
Form
Liquid
Description
Boster Bio Anti-VEGFR2/Flk-1 (phospho-Y1175) KDR Antibody catalog # A00901Y1175. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-VEGFR2/Flk-1 (phospho-Y1175) KDR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00901Y1175)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Flk-1 around the phosphorylation site of Y1059.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00901Y1175 is reactive to KDR in Human, Mouse, Rat
Applications
A00901Y1175 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
151.527kDa
Background of VEGFR2/KDR/Flk-1
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis By similarity.
McCauliffe D.P., J. Clin. Invest. 85:1379-1391(1990).
Rokeach L.A., J. Immunol. 147:3031-3039(1991).
McCauliffe D.P., J. Biol. Chem. 267:2557-2562(1992).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of KDR using Anti-VEGFR2/Flk-1 (phospho-Y1175) KDR Antibody (A00901Y1175).
Immunohistochemistry (IHC) analyzes of p-VEGFR2/Flk-1 (Y1175) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For KDR (Source: Uniprot.org, NCBI)
Gene Name
KDR
Full Name
Vascular endothelial growth factor receptor 2
Weight
151.527kDa
Superfamily
protein kinase superfamily
Alternative Names
CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2 KDR CD309, FLK1, VEGFR, VEGFR2 kinase insert domain receptor vascular endothelial growth factor receptor 2|fetal liver kinase-1|kinase insert domain receptor (a type III receptor tyrosine kinase)|protein-tyrosine kinase receptor Flk-1|soluble VEGFR2|tyrosine kinase growth factor receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KDR, check out the KDR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KDR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VEGFR2/Flk-1 (phospho-Y1175) KDR Antibody (A00901Y1175)
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No publications found for A00901Y1175
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