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Product Info Summary
| SKU: | A09816 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody
SKU/Catalog Number
A09816
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody (Catalog # A09816). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PLAGL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09816)
Host
Rabbit
Contents
PLAGL2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PLAGL2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PLAGL2. The immunogen is located within amino acids 40 - 90 of PLAGL2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms are known to exist.
Reactive Species
A09816 is reactive to PLAGL2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
54584 MW
Background of PLAGL2
The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09816 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PLAGL2 antibody can be used for detection of PLAGL2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PLAGL2 in rat brain tissue lysate with PLAGL2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of PLAGL2 in rat brain tissue with PLAGL2 antibody at 2 μg/ml.
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Immunofluorescence of PLAGL2 in rat brain tissue with PLAGL2 antibody at 20 μg/ml.
Green: PLAGL2 Antibody (A09816)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For PLAGL2 (Source: Uniprot.org, NCBI)
Gene Name
PLAGL2
Full Name
Zinc finger protein PLAGL2
Weight
54584 MW
Superfamily
krueppel C2H2-type zinc-finger protein family
Alternative Names
ZNF900, KIAA0198, Zinc finger protein PLAGL2, Pleiomorphic adenoma-like protein 2 PLAGL2 ZNF900 PLAG1 like zinc finger 2 zinc finger protein PLAGL2|C2H2-type zinc finger protein|pleiomorphic adenoma gene-like 2|pleiomorphic adenoma-like protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PLAGL2, check out the PLAGL2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PLAGL2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody (A09816)
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