APOBEC1 complementation factor (A1CF)

Essential component of the apolipoprotein B mRNA editing enzyme complex that's responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is likely responsible for docking the catalytic subunit, APOBEC1, to the mRNA to let it deaminate its target cytosine.

The complex also protects the edited APOB mRNA from nonsense-mediated decay. .