Anaphase-promoting complex subunit 15 (ANAPC15)

Component of the anaphase promoting complex/cyclosome (APC/C), a mobile cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. From the complex, plays a role in the release of the mitotic checkpoint complex (MCC) in the APC/C: not required for APC/C action itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint.

Also required for degradation of CDC20. .