V-type proton ATPase subunit H (ATP6V1H)

Subunit of the peripheral V1 complex of vacuolar ATPase.

Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow.

Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.