CBX6 Antibodies

AND CBX6 ELISA kits, CBX6 Proteins

Many biological assays use antibodies to detect CBX6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CBX6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CBX6 antibodies...

We validate the specificity of these antibodies to CBX6 by testing them on tissues known to express CBX6 positively and negatively. Browse below to find the CBX6 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CBX6 Infographic by Boster Bio

All CBX6 Products

Product

Figures

Specificity

Applications

Price

CBX6 Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1662
1 kit, containing one 96-well plate and all necessary reagents

Anti-CBX6 (K18) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A11651
100ul

Anti-Chromobox protein homolog 6 CBX6 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A11651-1
100ul

CBX6 (NM_014292) Human Over-expression Lysate

Human

$628
Cat # LS023466
100 µg

CBX6 Overview

Facts about Chromobox protein homolog 6.

CBX6 3D structure. Source: alphafold

Chromobox protein homolog 6 (CBX6)

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to keep the transcriptionally repressive state of several genes, such as Hox genes, throughout evolution (PubMed:21282530). PcG PRC1 complex acts through chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A'Lys-119', rendering chromatin heritably changed in its expressibility.

Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might happen in an H3K27me3-independent fashion (By similarity).

Gene Information

Human
Gene Name:	CBX6
Uniprot:	O95503
Entrez:	23466

Family

Belongs to:

No superfamily

Alternative Names

chromobox homolog 6; chromobox protein homolog 6

Molecular Weight

Mass (kDA):
43.898 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (38861422..38872216, complement)

Subcellular Localizations

Nucleus. Chromosome. Uniformely distributed in the nucleoplasm (PubMed:18927235). Localizes to the inactivated X chromosome in females (By similarity).

Diseases

Malignant Neoplasms
Bladder Neoplasm
Age Related Macular Degeneration
Alzheimer's Disease
Glaucoma
Malignant Neoplasm Of Urinary Bladder

Interacting Proteins

BMI1
MOV10
PCGF2
PCGF3
RING1

RNF2

Pathways

Cell Cycle
Localization
Protein Targeting
Metaphase
Regulation Of Gene Expression
Nuclear Export
Liver Development

Chromatin Remodeling
Histone Phosphorylation

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CBX6

References

PMID: 18927235 by Vincenz C., et al. Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences.

PMID: 21282530 by Vandamme J., et al. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells.