This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Cyclin-dependent kinase 14.
Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of these result remains to be verified in vivo.
Human | |
---|---|
Gene Name: | CDK14 |
Uniprot: | O94921 |
Entrez: | 5218 |
Belongs to: |
---|
protein kinase superfamily |
Cell division protein kinase 14; cyclin-dependent kinase 14; EC 2.7.11; KIAA0834EC 2.7.11.22; PFTAIRE1hPFTAIRE1; PFTK1PFTAIRE protein kinase 1; Serine/threonine-protein kinase PFTAIRE-1
Mass (kDA):
53.057 kDA
Human | |
---|---|
Location: | 7q21.13 |
Sequence: | 7; NC_000007.14 (90596321..91210590) |
Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected.
Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Recruited to the cell membrane by CCNY.
PMID: 11313143 by Yang T., et al. Identification and cellular localization of human PFTAIRE1.
PMID: 12098780 by Yang T., et al. KIAA0202, a human septin family member, interacting with hPFTAIRE1.