Drebrin-like protein Antibodies

AND Dbnl ELISA kits, Drebrin-like protein Proteins

Many biological assays use antibodies to detect Drebrin-like protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Drebrin-like protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Drebrin-like protein antibodies...

We validate the specificity of these antibodies to Drebrin-like protein by testing them on tissues known to express Dbnl positively and negatively. Browse below to find the Dbnl antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dbnl Infographic by Boster Bio

All Dbnl Products

Product

Figures

Specificity

Applications

Price

Anti-Drebrin-like protein DBNL Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05323
100ul

HIP55 (DBNL) (NM_001014436) Human Recombinant Protein

$1249
Cat # PROTQ9UJU6
20 µg

Anti-HIP55 (DBNL) Mouse Monoclonal Antibody [Clone ID: OTI6C9]

Human, Mouse, Rat

IHC

$523
Cat # M05323
100 µl

Anti-HIP55 (DBNL) Mouse Monoclonal Antibody [Clone ID: OTI7B7]

Human, Mouse, Rat

$523
Cat # M05323-1
100 µl

HIP55 (DBNL) (NM_014063) Human Over-expression Lysate

Human

$628
Cat # LS028988
100 µg

Dbnl Overview

Facts about Drebrin-like protein.

Drebrin-like protein (Dbnl)

Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL.

Does not bind G- actin and promote actin polymerization by itself. Required for the formation of coordinated podosome rosettes.

Gene Information

Mouse
Gene Name:	Dbnl
Uniprot:	Q62418
Entrez:	13169

Family

Belongs to:

ABP1 family

Alternative Names

ABP1; Cervical SH3P7; CMAP; drebrin-F; drebrin-like protein; drebrin-like; HIP-55SH3P7Cervical mucin-associated protein; HPK1-interacting protein of 55 kDa; SH3 domain-containing protein 7; src homology 3 domain-containing protein HIP-55

Molecular Weight

Mass (kDA):
48.7 kDA

Genomic Context


Mouse

Location:	11 A1\|11 3.87 cM
Sequence:	11;

Tissue Specificity

Detected in hippocampus neurons and in the Purkinje cell layer in cerebellum (at protein level). Predominantly expressed in brain, thymus and spleen. Also found in testis, heart and lung. Little or no expression detected in ovary or muscle.

Diseases

Tissue Adhesions
Extravasation
Cell Invasion
Deficiency Of Butyryl-coa Dehydrogenase
Cell Transformation, Neoplastic
Neurodegenerative Disorders
Epilepsy
Hypertensive Disease
Congenital Heart Defects
Yersinia Infections
Neoplasms
Headache

Pulmonary Emphysema
Convulsions
Inflammation
Lymphoma
Salmonella Infections
Status Epilepticus

Pathways

Endocytosis
Transport
Localization
Rna Interference
Clathrin-mediated Endocytosis
Receptor-mediated Endocytosis
Phagocytosis
Actin Cytoskeleton Organization
Cell Activation
Vesicle Transport
Cell Migration
T Cell Activation

Rna Splicing
Cytoskeleton Organization
Nuclear Migration
Cell Motility
Mitochondrial Fission
Interphase
Iron-sulfur Cluster Assembly

PTMs

Phosphorylation

Cleavage

Dephosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dbnl

References

PMID: 9630982 by Sparks A.B., et al. Cloning of ligand targets: systematic isolation of SH3 domain- containing proteins.

PMID: 9891087 by Larbolette O., et al. SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors.