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ELP5 Antibodies

AND ELP5 ELISA kits, ELP5 Proteins

Many biological assays use antibodies to detect ELP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ELP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ELP5 antibodies...

We validate the specificity of these antibodies to ELP5 by testing them on tissues known to express ELP5 positively and negatively. Browse below to find the ELP5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ELP5 Infographic by Boster Bio

ELP5 protein infographic

All ELP5 Products

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Product

Figures

Specificity

Applications

Price

Anti-Elongator complex protein 5 ELP5 Antibody

Western blot analysis of extracts of various cell lines, using ELP5 antibody at 1:1000 dilution

Western blot analysis of extracts of various cell lines, using ELP5 antibody at 1:1000 dilution

Human, Mouse

WB

$405
Cat # A11338
100ul

Human ELP5 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE

$265
Cat # PROTQ8TE02
Starting from 10ug

C17orf81 (ELP5) (NM_015362) Human Over-expression Lysate

C17orf81 (ELP5) Human Over-expression Lysates NM_015362

C17orf81 (ELP5) Human Over-expression Lysates NM_015362

C17orf81 (ELP5) Human Over-expression Lysates NM_203413

C17orf81 (ELP5) Human Over-expression Lysates NM_203414

Human

$628
Cat # LS023587
20 µg, 100 µg

ELP5 Overview

Facts about Elongator complex protein 5.

ELP5 3D structure

ELP5 3D structure. Source: alphafold

Elongator complex protein 5 (ELP5)

Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase part of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and likely H4.

Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation.

Gene Information

Human
Gene Name:	ELP5
Uniprot:	Q8TE02
Entrez:	23587

Gene Information

Family

Belongs to:

ELP5 family

Family

Alternative Names

chromosome 17 open reading frame 81; dermal papilla derived protein 6; dermal papilla-derived protein 6; DERP6; MST071; MSTP071; S-phase 2 protein

Molecular Weight

Mass (kDA):
34.841 kDA

Molecular Weight

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (7251737..7259940)

Tissue Specificity

Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis.

Subcellular Localizations

Nucleus. Cytoplasm.

Subcellular Localization

Diseases

Cell Invasion
Melanoma
Neurodegenerative Disorders
Poisoning
Neoplasm Invasiveness
Diphtheria

Disease

Interacting Proteins

ATXN1
ELP4

Interacting Proteins

Pathways

Trna Modification
Exocytosis
Cell Cycle
Histone Acetylation
Regulation Of Cell Cycle
Cytoskeleton Organization
Cell Migration

Translation
Cell Growth

Pathways

PTMs

Phosphorylation

Acetylation

Ribosylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELP5

References

PMID: 16850183 by Yuan J., et al. Cloning and characterization of the human gene DERP6, which activates transcriptional activities of p53.

PMID: 22854966 by Close P., et al. DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.