Fibroblast growth factor 2 (FGF2)

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:8663044).

Also acts as an integrin ligand that's required for FGF2 signaling (PubMed:28302677).

Binds to integrin ITGAV:ITGB3 (PubMed:28302677). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed:8663044, PubMed:28302677).