HTR6 Antibodies

AND HTR6 ELISA kits, HTR6 Proteins

Many biological assays use antibodies to detect HTR6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HTR6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HTR6 antibodies...

We validate the specificity of these antibodies to HTR6 by testing them on tissues known to express HTR6 positively and negatively. Browse below to find the HTR6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HTR6 Infographic by Boster Bio

All HTR6 Products

Product

Figures

Specificity

Applications

Price

Anti-5-HT-6 HTR6 Antibody

1 Citations 1 Q&As

Human

$360
Cat # A11122
100 µl

Anti-SR-6 HTR6 Antibody

4 Q&As

Human, Mouse, Rat

$399
Cat # A11122-1
100μl

5HT6 Receptor (HTR6) (NM_000871) Human Over-expression Lysate

Human

$628
Cat # LS003362
100 µg

HTR6 Overview

Facts about 5-hydroxytryptamine receptor 6.

HTR6 3D structure. Source: alphafold

5-hydroxytryptamine receptor 6 (HTR6)

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity).

Gene Information

Human
Gene Name:	HTR6
Uniprot:	P50406
Entrez:	3362

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

5-HT6; 5-hydroxytryptamine (serotonin) receptor 6,5-HT65-HT6R; HTR6; Serotonin receptor 6,5-HT-6,5-hydroxytryptamine receptor 6

Molecular Weight

Mass (kDA):
46.954 kDA

Genomic Context


Human

Location:	1p36.13
Sequence:	1; NC_000001.11 (19664875..19680966)

Tissue Specificity

Expressed in several human brain regions, most prominently in the caudate nucleus.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Schizophrenia
Major Depressive Disorder
Depressive Disorder
Mood Disorders
Malignant Neoplasms
Attention Deficit Hyperactivity Disorder
Anxiety Disorders
Psychotic Disorders
Obesity
Alzheimer's Disease
Sclerosis
Retinal Degeneration
Dementia

Hypokinesia
Dyskinetic Syndrome
Inattention
Nervousness
Dyskinesia, Drug-induced
Blunted Affect
Paranoid Schizophrenia

Interacting Proteins

Pathways

Response To Risperidone
Localization
Transport
Methylation
Response To Clozapine
Cellular Localization
Prepulse Inhibition
Brain Development
Feeding Behavior

Regulation Of Gene Expression
Cognition
Pathogenesis

PTMs

Methylation

Research Areas

GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HTR6

References

PMID: 8522988 by Kohen R., et al. Cloning, characterization, and chromosomal localization of a human 5- HT6 serotonin receptor.

PMID: 7656980 by Ullmer C., et al. Expression of serotonin receptor mRNAs in blood vessels.

1 Publications of Boster HTR6 Antibodies & ELISA Kits

PubMed ID: 30315688, Ren S,Chen M,Yang L,Liu Z.5-Hydroxytryptamine and Dopamine Neurons in the Cerebe...

*More publications can be found for each product on its corresponding product page